Highly glycosylated MUC1 mediates high affinity L-selectin binding at the human endometrial surface

Highly glycosylated MUC1 mediates high affinity L-selectin binding at the human endometrial surface

Abstract Background Sialyl-Lewis X/L-selectin high affinity binding interactions between transmembrane O-glycosylated mucins proteins and the embryo have been implicated in implantation processes within the human reproductive system. However, the adhesive properties of these mucins at the endometria...

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Bibliographic Details
Main Authors: Lewis W. Francis, Seydou N. Yao, Lydia C. Powell, Sean Griffiths, Alexander Berquand, Thomas Piasecki, William Howe, Andrea S. Gazze, Mary C. Farach-Carson, Pamela Constantinou, Daniel Carson, Lavinia Margarit, Deya Gonzalez, R. Steven Conlan
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Nanobiotechnology
Subjects:
Adhesion
Single molecule force spectroscopy
Mucin
Implantation
Biophysics
Human reproduction
Online Access:https://doi.org/10.1186/s12951-021-00793-9

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