Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis
Hepatocellular carcinoma (HCC) is frequently associated with macrovascular invasion of the portal vein or hepatic veins in advanced stages. The accurate diagnosis of macrovascular invasion and the differentiation from bland non-tumoral thrombus has significant clinical and management implications, s...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2020-11-01
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| Series: | Diagnostic and Interventional Radiology |
| Online Access: |
http://www.dirjournal.org/archives/archive-detail/article-preview/hepatocellular-carcinoma-with-macrovascular-invasi/54618
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| _version_ | 1797691277961068544 |
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| author | Roberto Cannella Adele Taibbi Giorgia Porrello Marco Dioguardi Burgio Giuseppe Cabibbo Tommaso Vincenzo Bartolotta |
| author_facet | Roberto Cannella Adele Taibbi Giorgia Porrello Marco Dioguardi Burgio Giuseppe Cabibbo Tommaso Vincenzo Bartolotta |
| author_sort | Roberto Cannella |
| collection | DOAJ |
| description | Hepatocellular carcinoma (HCC) is frequently associated with macrovascular invasion of the portal vein or hepatic veins in advanced stages. The accurate diagnosis of macrovascular invasion and the differentiation from bland non-tumoral thrombus has significant clinical and management implications, since it narrows the therapeutic options and it represents a mandatory contraindication for liver resection or transplantation. The imaging diagnosis remains particularly challenging since the imaging features of HCC with macrovascular invasion may be subtle, especially in lesions showing infiltrative appearance. However, each radiologic imaging modality may provide findings suggesting the presence of tumor thrombus rather than bland thrombus. The purpose of this paper is to review the current guidelines and imaging appearance of HCC with macrovascular invasion. Knowledge of the most common imaging features of HCC with macrovascular invasion may improve the diagnostic confidence of tumor thrombus in clinical practice and help to guide patients’ management. |
| first_indexed | 2024-03-12T02:12:08Z |
| format | Article |
| id | doaj.art-5b77653769f8482c80338654652e8047 |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-03-12T02:12:08Z |
| publishDate | 2020-11-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-5b77653769f8482c80338654652e80472023-09-06T13:00:21ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122020-11-0126653154010.5152/dir.2020.1956913049054Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosisRoberto Cannella0Adele Taibbi1Giorgia Porrello2Marco Dioguardi Burgio3Giuseppe Cabibbo4Tommaso Vincenzo Bartolotta5 Department of Radiology - BiND, University Hospital “Paolo Giaccone”, Palermo, Italy Department of Radiology - BiND, University Hospital “Paolo Giaccone”, Palermo, Italy Department of Radiology - BiND, University Hospital “Paolo Giaccone”, Palermo, Italy Department of Radiology, AP-HP, Hôpital Beaujon, Clichy, Hauts-de-Seine, France Department of Health Promotion, Division of Gastroenterology and Hepatology, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy Department of Radiology - BiND, University Hospital “Paolo Giaccone”, Palermo, Italy Hepatocellular carcinoma (HCC) is frequently associated with macrovascular invasion of the portal vein or hepatic veins in advanced stages. The accurate diagnosis of macrovascular invasion and the differentiation from bland non-tumoral thrombus has significant clinical and management implications, since it narrows the therapeutic options and it represents a mandatory contraindication for liver resection or transplantation. The imaging diagnosis remains particularly challenging since the imaging features of HCC with macrovascular invasion may be subtle, especially in lesions showing infiltrative appearance. However, each radiologic imaging modality may provide findings suggesting the presence of tumor thrombus rather than bland thrombus. The purpose of this paper is to review the current guidelines and imaging appearance of HCC with macrovascular invasion. Knowledge of the most common imaging features of HCC with macrovascular invasion may improve the diagnostic confidence of tumor thrombus in clinical practice and help to guide patients’ management. http://www.dirjournal.org/archives/archive-detail/article-preview/hepatocellular-carcinoma-with-macrovascular-invasi/54618 |
| spellingShingle | Roberto Cannella Adele Taibbi Giorgia Porrello Marco Dioguardi Burgio Giuseppe Cabibbo Tommaso Vincenzo Bartolotta Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis Diagnostic and Interventional Radiology |
| title | Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis |
| title_full | Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis |
| title_fullStr | Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis |
| title_full_unstemmed | Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis |
| title_short | Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis |
| title_sort | hepatocellular carcinoma with macrovascular invasion multimodality imaging features for the diagnosis |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/hepatocellular-carcinoma-with-macrovascular-invasi/54618
|
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