Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report
BackgroundNocardiosis is an opportunistic infection that primarily affects immunocompromised patients. Pulmonary nocardiosis is the most prevalent form, but can also spread to other organs. Potential causes contributing to opportunistic infection may include immunosuppression and disruption of tight...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1266857/full |
| _version_ | 1797688232964521984 |
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| author | Liming Cao Yilan Sun Fei Chen |
| author_facet | Liming Cao Yilan Sun Fei Chen |
| author_sort | Liming Cao |
| collection | DOAJ |
| description | BackgroundNocardiosis is an opportunistic infection that primarily affects immunocompromised patients. Pulmonary nocardiosis is the most prevalent form, but can also spread to other organs. Potential causes contributing to opportunistic infection may include immunosuppression and disruption of tight junctions, both of which can result from COVID-19.Case presentationWe reported a case of a 68-year-old male patient who presented with a 10-day history of fever, cough, and productive sputum. Upon physical examination, velcro rales were detected in the right lung, while breath sounds in the left lung were clear. The patient had previously undergone left lung transplantation due to idiopathic pulmonary fibrosis four years ago. He was initially hospitalized and treated for COVID-19 but was readmitted due to worsening symptoms. Subsequently, pulmonary nocardiosis was diagnosed utilizing metagenomic next-generation sequencing of bronchoalveolar lavage fluid. The above-mentioned condition was improved following treatment with cancidas and linezolid. Now, he is under regular follow-up.ConclusionThis case highlights the complexity of COVID-19 and the occurrence of secondary opportunistic infections, which require further investigation. |
| first_indexed | 2024-03-12T01:29:14Z |
| format | Article |
| id | doaj.art-5b78596672ad4ddbbb37f69282885dda |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-03-12T01:29:14Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-5b78596672ad4ddbbb37f69282885dda2023-09-12T09:27:16ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-09-011010.3389/fmed.2023.12668571266857Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case reportLiming CaoYilan SunFei ChenBackgroundNocardiosis is an opportunistic infection that primarily affects immunocompromised patients. Pulmonary nocardiosis is the most prevalent form, but can also spread to other organs. Potential causes contributing to opportunistic infection may include immunosuppression and disruption of tight junctions, both of which can result from COVID-19.Case presentationWe reported a case of a 68-year-old male patient who presented with a 10-day history of fever, cough, and productive sputum. Upon physical examination, velcro rales were detected in the right lung, while breath sounds in the left lung were clear. The patient had previously undergone left lung transplantation due to idiopathic pulmonary fibrosis four years ago. He was initially hospitalized and treated for COVID-19 but was readmitted due to worsening symptoms. Subsequently, pulmonary nocardiosis was diagnosed utilizing metagenomic next-generation sequencing of bronchoalveolar lavage fluid. The above-mentioned condition was improved following treatment with cancidas and linezolid. Now, he is under regular follow-up.ConclusionThis case highlights the complexity of COVID-19 and the occurrence of secondary opportunistic infections, which require further investigation.https://www.frontiersin.org/articles/10.3389/fmed.2023.1266857/fullpulmonary nocardiosisCOVID-19idiopathic pulmonary fibrosislung transplantationimmunosuppression |
| spellingShingle | Liming Cao Yilan Sun Fei Chen Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report Frontiers in Medicine pulmonary nocardiosis COVID-19 idiopathic pulmonary fibrosis lung transplantation immunosuppression |
| title | Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report |
| title_full | Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report |
| title_fullStr | Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report |
| title_full_unstemmed | Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report |
| title_short | Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report |
| title_sort | pulmonary nocardiosis following covid 19 in a patient with idiopathic pulmonary fibrosis and lung transplantation a case report |
| topic | pulmonary nocardiosis COVID-19 idiopathic pulmonary fibrosis lung transplantation immunosuppression |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1266857/full |
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