HEPARIN INDUCED THROMBOCYTOPENIA
BACKGROUND Unfractionated heparin and low-molecular-weight-heparins are commonly prescribed drugsin everyday clinical practice for treatment or prevention of thrombotic diseases. Heparinis used also for providing patency of various catheters. Heparin seldom causes heparininduced thrombocytopenia (HI...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Medical Association
2008-03-01
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| Series: | Zdravniški Vestnik |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/915 |
| _version_ | 1811326395066875904 |
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| author | Matija Kozak Tadeja Dovč Drnovšek Tanja Gmeiner Stopar |
| author_facet | Matija Kozak Tadeja Dovč Drnovšek Tanja Gmeiner Stopar |
| author_sort | Matija Kozak |
| collection | DOAJ |
| description | BACKGROUND
Unfractionated heparin and low-molecular-weight-heparins are commonly prescribed drugsin everyday clinical practice for treatment or prevention of thrombotic diseases. Heparinis used also for providing patency of various catheters. Heparin seldom causes heparininduced thrombocytopenia (HIT) and concomitant activation of coagulation cascade.Activated coagulation could result in arterial or venous thrombosis.
CONCLUSIONS
Unrecognized HIT could be fatal. In HIT diagnostics regular follow-up of platelet values isimportant. When platelet number is decreasing, possibility of HIT should be taken intoaccount. After assessment of the clinical scoring system in HIT probable cases specific testsshould be done. When HIT is confirmed, patients should be treated with anticoagulants.Cumarins should not be used at the beginning, but later in patients with confirmed thromboticevent |
| first_indexed | 2024-04-13T14:49:48Z |
| format | Article |
| id | doaj.art-5b79587f48264570b24f10cd76bc8e1f |
| institution | Directory Open Access Journal |
| issn | 1318-0347 1581-0224 |
| language | English |
| last_indexed | 2024-04-13T14:49:48Z |
| publishDate | 2008-03-01 |
| publisher | Slovenian Medical Association |
| record_format | Article |
| series | Zdravniški Vestnik |
| spelling | doaj.art-5b79587f48264570b24f10cd76bc8e1f2022-12-22T02:42:39ZengSlovenian Medical AssociationZdravniški Vestnik1318-03471581-02242008-03-01773793HEPARIN INDUCED THROMBOCYTOPENIAMatija KozakTadeja Dovč DrnovšekTanja Gmeiner StoparBACKGROUND Unfractionated heparin and low-molecular-weight-heparins are commonly prescribed drugsin everyday clinical practice for treatment or prevention of thrombotic diseases. Heparinis used also for providing patency of various catheters. Heparin seldom causes heparininduced thrombocytopenia (HIT) and concomitant activation of coagulation cascade.Activated coagulation could result in arterial or venous thrombosis. CONCLUSIONS Unrecognized HIT could be fatal. In HIT diagnostics regular follow-up of platelet values isimportant. When platelet number is decreasing, possibility of HIT should be taken intoaccount. After assessment of the clinical scoring system in HIT probable cases specific testsshould be done. When HIT is confirmed, patients should be treated with anticoagulants.Cumarins should not be used at the beginning, but later in patients with confirmed thromboticeventhttp://vestnik.szd.si/index.php/ZdravVest/article/view/915 |
| spellingShingle | Matija Kozak Tadeja Dovč Drnovšek Tanja Gmeiner Stopar HEPARIN INDUCED THROMBOCYTOPENIA Zdravniški Vestnik |
| title | HEPARIN INDUCED THROMBOCYTOPENIA |
| title_full | HEPARIN INDUCED THROMBOCYTOPENIA |
| title_fullStr | HEPARIN INDUCED THROMBOCYTOPENIA |
| title_full_unstemmed | HEPARIN INDUCED THROMBOCYTOPENIA |
| title_short | HEPARIN INDUCED THROMBOCYTOPENIA |
| title_sort | heparin induced thrombocytopenia |
| url | http://vestnik.szd.si/index.php/ZdravVest/article/view/915 |
| work_keys_str_mv | AT matijakozak heparininducedthrombocytopenia AT tadejadovcdrnovsek heparininducedthrombocytopenia AT tanjagmeinerstopar heparininducedthrombocytopenia |