Helicobacter pylori infection amongst Arab Israeli women with hyperemesis gravidarum—a prospective, controlled study
Objective: Helicobacter pylori has been associated with hyperemesis gravidarum in some geographical regions. The prevalence of H. pylori in Arab Israeli women in the Upper Galilee and its association with hyperemesis gravidarum has not been studied previously. We aimed to examine if hyperemesis grav...
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| Format: | Article |
| Language: | English |
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Elsevier
2014-12-01
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| Series: | International Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971214016518 |
| _version_ | 1811294438140411904 |
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| author | Doron Boltin Tsachi Tsadok Perets Sami Abu Elheiga Asher Sharony Yaron Niv Hussein Shamaly Ram Dickman |
| author_facet | Doron Boltin Tsachi Tsadok Perets Sami Abu Elheiga Asher Sharony Yaron Niv Hussein Shamaly Ram Dickman |
| author_sort | Doron Boltin |
| collection | DOAJ |
| description | Objective: Helicobacter pylori has been associated with hyperemesis gravidarum in some geographical regions. The prevalence of H. pylori in Arab Israeli women in the Upper Galilee and its association with hyperemesis gravidarum has not been studied previously. We aimed to examine if hyperemesis gravidarum is associated with H. pylori in this population.
Methods: Subjects with hyperemesis gravidarum carrying a singleton fetus were recruited prospectively. Women with an uncomplicated pregnancy served as controls. All patients underwent 13C-urea breath testing to assess for H. pylori infection.
Results: A total of 72 subjects, including 24 patients with hyperemesis gravidarum and 48 controls, aged 28.8 ± 5.3 years, were included. H. pylori infection was identified in 75.0% (18/24) of cases and 60.4% (29/48) of controls (p = not significant). H. pylori infection did not correlate with age, fetal sex, or the number of previous pregnancies (p = not significant).
Conclusion: H. pylori does not seem to increase the likelihood of hyperemesis gravidarum in Arab Israeli women. However, given the high background prevalence of H. pylori in this population, a larger study is required to corroborate these findings. (MOH20110066) |
| first_indexed | 2024-04-13T05:17:24Z |
| format | Article |
| id | doaj.art-5b7983301a4d48aba4443ed2766ea5e3 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 1878-3511 |
| language | English |
| last_indexed | 2024-04-13T05:17:24Z |
| publishDate | 2014-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-5b7983301a4d48aba4443ed2766ea5e32022-12-22T03:00:51ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112014-12-0129C29229510.1016/j.ijid.2014.10.005Helicobacter pylori infection amongst Arab Israeli women with hyperemesis gravidarum—a prospective, controlled studyDoron Boltin0Tsachi Tsadok Perets1Sami Abu Elheiga2Asher Sharony3Yaron Niv4Hussein Shamaly5Ram Dickman6Department of Gastroenterology, Rabin Medical Center, Beilinson Campus, 39 Jabotinski Street, Petah Tikva, Israel 49100Gastroenterology Laboratory, Rabin Medical Center, Beilinson Campus, Petah Tikva, IsraelDepartment of Pediatric Gastroenterology, St Vincent French Hospital, Nazareth, IsraelRappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, IsraelDepartment of Gastroenterology, Rabin Medical Center, Beilinson Campus, 39 Jabotinski Street, Petah Tikva, Israel 49100Department of Pediatric Gastroenterology, St Vincent French Hospital, Nazareth, IsraelDepartment of Gastroenterology, Rabin Medical Center, Beilinson Campus, 39 Jabotinski Street, Petah Tikva, Israel 49100Objective: Helicobacter pylori has been associated with hyperemesis gravidarum in some geographical regions. The prevalence of H. pylori in Arab Israeli women in the Upper Galilee and its association with hyperemesis gravidarum has not been studied previously. We aimed to examine if hyperemesis gravidarum is associated with H. pylori in this population. Methods: Subjects with hyperemesis gravidarum carrying a singleton fetus were recruited prospectively. Women with an uncomplicated pregnancy served as controls. All patients underwent 13C-urea breath testing to assess for H. pylori infection. Results: A total of 72 subjects, including 24 patients with hyperemesis gravidarum and 48 controls, aged 28.8 ± 5.3 years, were included. H. pylori infection was identified in 75.0% (18/24) of cases and 60.4% (29/48) of controls (p = not significant). H. pylori infection did not correlate with age, fetal sex, or the number of previous pregnancies (p = not significant). Conclusion: H. pylori does not seem to increase the likelihood of hyperemesis gravidarum in Arab Israeli women. However, given the high background prevalence of H. pylori in this population, a larger study is required to corroborate these findings. (MOH20110066)http://www.sciencedirect.com/science/article/pii/S1201971214016518Helicobacter pyloriVomitingHyperemesis gravidarumPregnancy |
| spellingShingle | Doron Boltin Tsachi Tsadok Perets Sami Abu Elheiga Asher Sharony Yaron Niv Hussein Shamaly Ram Dickman Helicobacter pylori infection amongst Arab Israeli women with hyperemesis gravidarum—a prospective, controlled study International Journal of Infectious Diseases Helicobacter pylori Vomiting Hyperemesis gravidarum Pregnancy |
| title | Helicobacter pylori infection amongst Arab Israeli women with hyperemesis gravidarum—a prospective, controlled study |
| title_full | Helicobacter pylori infection amongst Arab Israeli women with hyperemesis gravidarum—a prospective, controlled study |
| title_fullStr | Helicobacter pylori infection amongst Arab Israeli women with hyperemesis gravidarum—a prospective, controlled study |
| title_full_unstemmed | Helicobacter pylori infection amongst Arab Israeli women with hyperemesis gravidarum—a prospective, controlled study |
| title_short | Helicobacter pylori infection amongst Arab Israeli women with hyperemesis gravidarum—a prospective, controlled study |
| title_sort | helicobacter pylori infection amongst arab israeli women with hyperemesis gravidarum a prospective controlled study |
| topic | Helicobacter pylori Vomiting Hyperemesis gravidarum Pregnancy |
| url | http://www.sciencedirect.com/science/article/pii/S1201971214016518 |
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