Primary Resistance to EGFR Tyrosine Kinase Inhibitors (TKIs): Contexts and Comparisons in EGFR-Mutated Lung Cancer

The discovery of the efficacy of tyrosine kinase inhibitors (TKIs) in epidermal growth factor receptor (<i>EGFR</i>)-mutated non-small-cell lung cancer (NSCLC) patients has revolutionized lung cancer therapy. Although almost all responders acquire drug resistance within a few years, many...

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Bibliographic Details
Main Author: Keigo Kobayashi
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Journal of Respiration
Subjects:
Online Access:https://www.mdpi.com/2673-527X/3/4/21