Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.

<h4>Objective</h4>Polypharmacy, defined as the concurrent use of multiple medications, is a growing concern globally. This study aimed to identify the significant factors that predict the perceived burden of medication and health-related quality of life.<h4>Methods</h4>Adults...

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Main Authors: Won Sun Chen, Md Rafiqul Islam, Sajini Ambepitiya, William Sim, Wai Yiu, Joseph Carey, Edward Ogden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0267593
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author Won Sun Chen
Md Rafiqul Islam
Sajini Ambepitiya
William Sim
Wai Yiu
Joseph Carey
Edward Ogden
author_facet Won Sun Chen
Md Rafiqul Islam
Sajini Ambepitiya
William Sim
Wai Yiu
Joseph Carey
Edward Ogden
author_sort Won Sun Chen
collection DOAJ
description <h4>Objective</h4>Polypharmacy, defined as the concurrent use of multiple medications, is a growing concern globally. This study aimed to identify the significant factors that predict the perceived burden of medication and health-related quality of life.<h4>Methods</h4>Adults, aged 18 years and above who have used at least two regular medicines, were invited to complete the study questionnaires between June and October 2019. Multiple linear regression analysis was conducted to identify significant predictors for perceived burden of medication and health-related quality of life.<h4>Results</h4>A total of 119 participants completed this study. The average age of the participants was 63 years (SD±16 years). Factors significantly predicting perceived burden of medication were participants' current health condition (p = 0.001), overall burden of treatment (p<0.001) and being hypertensive (p = 0.037). Similarly, participants' current health condition (p<0.001) and overall burden of treatment (p = 0.086) were significant predictors for perceived health-related quality of life.<h4>Conclusions</h4>This study revealed that hypertensive participants in poor health tended to experience higher perceived burden of medication, which in turn was found to be correlated with lower perceived health-related quality of life.
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spelling doaj.art-5b7aa529866b4df6bc9b213c87ef758f2022-12-22T00:43:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01174e026759310.1371/journal.pone.0267593Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.Won Sun ChenMd Rafiqul IslamSajini AmbepitiyaWilliam SimWai YiuJoseph CareyEdward Ogden<h4>Objective</h4>Polypharmacy, defined as the concurrent use of multiple medications, is a growing concern globally. This study aimed to identify the significant factors that predict the perceived burden of medication and health-related quality of life.<h4>Methods</h4>Adults, aged 18 years and above who have used at least two regular medicines, were invited to complete the study questionnaires between June and October 2019. Multiple linear regression analysis was conducted to identify significant predictors for perceived burden of medication and health-related quality of life.<h4>Results</h4>A total of 119 participants completed this study. The average age of the participants was 63 years (SD±16 years). Factors significantly predicting perceived burden of medication were participants' current health condition (p = 0.001), overall burden of treatment (p<0.001) and being hypertensive (p = 0.037). Similarly, participants' current health condition (p<0.001) and overall burden of treatment (p = 0.086) were significant predictors for perceived health-related quality of life.<h4>Conclusions</h4>This study revealed that hypertensive participants in poor health tended to experience higher perceived burden of medication, which in turn was found to be correlated with lower perceived health-related quality of life.https://doi.org/10.1371/journal.pone.0267593
spellingShingle Won Sun Chen
Md Rafiqul Islam
Sajini Ambepitiya
William Sim
Wai Yiu
Joseph Carey
Edward Ogden
Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.
PLoS ONE
title Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.
title_full Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.
title_fullStr Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.
title_full_unstemmed Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.
title_short Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.
title_sort factors associated with patient experiences of the burden of using medicines and health related quality of life a cross sectional study
url https://doi.org/10.1371/journal.pone.0267593
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