Fatty Acid Modification of the Anticancer Peptide LVTX-9 to Enhance Its Cytotoxicity against Malignant Melanoma Cells

Fatty Acid Modification of the Anticancer Peptide LVTX-9 to Enhance Its Cytotoxicity against Malignant Melanoma Cells

Spider venom is a valuable resource for the development of novel anticancer drugs. In this study, we focused on novel linear amphipathic α-helical anticancer peptide LVTX-9, which was derived from the cDNA library of the venom gland of the spider <i>Lycosa vittata</i>. The cytotoxicity o...

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Bibliographic Details
Main Authors: Fengjiao Li, Saizhi Wu, Ninglin Chen, Jingyu Zhu, Xinxin Zhao, Peng Zhang, Youlin Zeng, Zhonghua Liu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Toxins
Subjects:
spider venom
anticancer peptides
LVTX-9
fatty acids modification
cytotoxicity
3D B16-F10 spheroids
Online Access:https://www.mdpi.com/2072-6651/13/12/867

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