The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational Study
<i>Background and Objectives:</i> Malignant neoplasms are common causes of acute pleuropericardial effusion. Pleuropericarditis denotes poor patient prognosis, is associated with shortened average survival time, and represents a surgical emergency. <i>Materials and Methods:</i&g...
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MDPI AG
2022-05-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/6/718 |
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| author | Claudiu-Eduard Nistor Camelia Stanciu Găvan Alexandra-Andreea Ciritel Alexandra Floriana Nemes Adrian Ciuche |
| author_facet | Claudiu-Eduard Nistor Camelia Stanciu Găvan Alexandra-Andreea Ciritel Alexandra Floriana Nemes Adrian Ciuche |
| author_sort | Claudiu-Eduard Nistor |
| collection | DOAJ |
| description | <i>Background and Objectives:</i> Malignant neoplasms are common causes of acute pleuropericardial effusion. Pleuropericarditis denotes poor patient prognosis, is associated with shortened average survival time, and represents a surgical emergency. <i>Materials and Methods:</i> We analyzed the impact of two minimally invasive surgical approaches, the type of cancer, and other clinical variables on the mortality of 338 patients with pleuropericarditis admitted to an emergency hospital in Romania between 2009 and 2020. All patients underwent minimally invasive surgeries to prevent the recurrence of the disease and to increase their life expectancy. Log-rank tests were used to check for survival probability differences by surgical approach. We also applied univariate and multivariate Cox proportional hazard models to assess the effect of each covariate. <i>Results:</i> No significant differences were found in the 2-year overall survival rate between patients who underwent the two types of surgery. The multivariate Cox proportional regression model adjusted for relevant covariates showed that age, having lung cancer, and a diagnosis of pericarditis and right pleural effusion increased the mortality risk. The surgical approach was not associated with mortality in these patients. <i>Conclusion:</i> These findings open up avenues for future research to advance the understanding of survival among patients with pleuropericarditis. |
| first_indexed | 2024-03-09T23:06:50Z |
| format | Article |
| id | doaj.art-5b7c7406531b4b03a3c0d6437255b144 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T23:06:50Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-5b7c7406531b4b03a3c0d6437255b1442023-11-23T17:51:20ZengMDPI AGMedicina1010-660X1648-91442022-05-0158671810.3390/medicina58060718The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational StudyClaudiu-Eduard Nistor0Camelia Stanciu Găvan1Alexandra-Andreea Ciritel2Alexandra Floriana Nemes3Adrian Ciuche4Department of Thoracic Surgery, Central Military Emergency University Hospital Bucharest, University of Medicine and Pharmacy “Carol Davila”, 010825 Bucharest, RomaniaDepartment of Thoracic Surgery, Central Military Emergency University Hospital Bucharest, University of Medicine and Pharmacy “Carol Davila”, 010825 Bucharest, RomaniaFamily and Fertility Department, ESRC Centre for Population Change, Building 58, Room 2001, Faculty of Social Sciences, University of Southampton, Southampton SO17 1TW, UKDepartment of Neonatology, Louis Ţurcanu Clinical Emergency Hospital for Children, 300011 Timişoara, RomaniaDepartment of Thoracic Surgery, Central Military Emergency University Hospital Bucharest, University of Medicine and Pharmacy “Carol Davila”, 010825 Bucharest, Romania<i>Background and Objectives:</i> Malignant neoplasms are common causes of acute pleuropericardial effusion. Pleuropericarditis denotes poor patient prognosis, is associated with shortened average survival time, and represents a surgical emergency. <i>Materials and Methods:</i> We analyzed the impact of two minimally invasive surgical approaches, the type of cancer, and other clinical variables on the mortality of 338 patients with pleuropericarditis admitted to an emergency hospital in Romania between 2009 and 2020. All patients underwent minimally invasive surgeries to prevent the recurrence of the disease and to increase their life expectancy. Log-rank tests were used to check for survival probability differences by surgical approach. We also applied univariate and multivariate Cox proportional hazard models to assess the effect of each covariate. <i>Results:</i> No significant differences were found in the 2-year overall survival rate between patients who underwent the two types of surgery. The multivariate Cox proportional regression model adjusted for relevant covariates showed that age, having lung cancer, and a diagnosis of pericarditis and right pleural effusion increased the mortality risk. The surgical approach was not associated with mortality in these patients. <i>Conclusion:</i> These findings open up avenues for future research to advance the understanding of survival among patients with pleuropericarditis.https://www.mdpi.com/1648-9144/58/6/718malignant pleuropericarditisminimal invasive surgerysurvival analysis |
| spellingShingle | Claudiu-Eduard Nistor Camelia Stanciu Găvan Alexandra-Andreea Ciritel Alexandra Floriana Nemes Adrian Ciuche The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational Study Medicina malignant pleuropericarditis minimal invasive surgery survival analysis |
| title | The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational Study |
| title_full | The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational Study |
| title_fullStr | The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational Study |
| title_full_unstemmed | The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational Study |
| title_short | The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational Study |
| title_sort | association of minimally invasive surgical approaches and mortality in patients with malignant pleuropericarditis a 10 year retrospective observational study |
| topic | malignant pleuropericarditis minimal invasive surgery survival analysis |
| url | https://www.mdpi.com/1648-9144/58/6/718 |
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