National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020

(1) Background: To describe trends in the prevalence of depression in men and women with COPD hospitalized in Spain (2016–2020). (2) Methods: We used a nationwide discharge database to select all patients ≥35 years with COPD. (3) Results: The prevalence of depression was 3.54-times higher in women w...

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Main Authors: Javier de Miguel-Díez, Ana Lopez-de-Andres, Rodrigo Jimenez-Garcia, Jose M. de Miguel-Yanes, Valentin Hernández-Barrera, David Carabantes-Alarcon, Jose J. Zamorano-Leon, Concepcion Noriega
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/21/6337
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author Javier de Miguel-Díez
Ana Lopez-de-Andres
Rodrigo Jimenez-Garcia
Jose M. de Miguel-Yanes
Valentin Hernández-Barrera
David Carabantes-Alarcon
Jose J. Zamorano-Leon
Concepcion Noriega
author_facet Javier de Miguel-Díez
Ana Lopez-de-Andres
Rodrigo Jimenez-Garcia
Jose M. de Miguel-Yanes
Valentin Hernández-Barrera
David Carabantes-Alarcon
Jose J. Zamorano-Leon
Concepcion Noriega
author_sort Javier de Miguel-Díez
collection DOAJ
description (1) Background: To describe trends in the prevalence of depression in men and women with COPD hospitalized in Spain (2016–2020). (2) Methods: We used a nationwide discharge database to select all patients ≥35 years with COPD. (3) Results: The prevalence of depression was 3.54-times higher in women with COPD than in men (OR 3.54; 95%CI 3.48–3.6). It decreased significantly between 2016 and 2020, although the reduction was only significant in women (12.27% in 2016 vs. 10.56% in 2020). Older age, comorbidity and the most recent years of hospital admission were associated with lower prevalence of depression in both men and women, while obesity, obstructive sleep apnea (OSA) and use of oxygen prior to admission were risk factors. In-hospital mortality (IHM) increased significantly over time. Older age, comorbidity, the use of oxygen prior to admission and having been hospitalized in 2020 increased the risk of IHM. Female sex was associated with a lower IHM in patients with depression and COPD. (4) Conclusions: The prevalence of depression has decreased over time in women with COPD while it has not changed significantly in men with this disease. IHM increased over time both in men and women with COPD and depression, with higher prevalence in the former.
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spelling doaj.art-5b7f1ba277b04c4591f9b2845825deb92023-11-24T05:16:07ZengMDPI AGJournal of Clinical Medicine2077-03832022-10-011121633710.3390/jcm11216337National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020Javier de Miguel-Díez0Ana Lopez-de-Andres1Rodrigo Jimenez-Garcia2Jose M. de Miguel-Yanes3Valentin Hernández-Barrera4David Carabantes-Alarcon5Jose J. Zamorano-Leon6Concepcion Noriega7Respiratory Department, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Universidad Complutense de Madrid, 28009 Madrid, SpainDepartment of Public Health and Maternal & Child Health, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, SpainDepartment of Public Health and Maternal & Child Health, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, SpainInternal Medicine Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Universidad Complutense de Madrid, 28009 Madrid, SpainPreventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Public Health and Maternal & Child Health, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, SpainDepartment of Public Health and Maternal & Child Health, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, SpainDepartment of Nursery and Physiotherapy, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcalá de Henares, Spain(1) Background: To describe trends in the prevalence of depression in men and women with COPD hospitalized in Spain (2016–2020). (2) Methods: We used a nationwide discharge database to select all patients ≥35 years with COPD. (3) Results: The prevalence of depression was 3.54-times higher in women with COPD than in men (OR 3.54; 95%CI 3.48–3.6). It decreased significantly between 2016 and 2020, although the reduction was only significant in women (12.27% in 2016 vs. 10.56% in 2020). Older age, comorbidity and the most recent years of hospital admission were associated with lower prevalence of depression in both men and women, while obesity, obstructive sleep apnea (OSA) and use of oxygen prior to admission were risk factors. In-hospital mortality (IHM) increased significantly over time. Older age, comorbidity, the use of oxygen prior to admission and having been hospitalized in 2020 increased the risk of IHM. Female sex was associated with a lower IHM in patients with depression and COPD. (4) Conclusions: The prevalence of depression has decreased over time in women with COPD while it has not changed significantly in men with this disease. IHM increased over time both in men and women with COPD and depression, with higher prevalence in the former.https://www.mdpi.com/2077-0383/11/21/6337COPDdepressionsexprevalencein-hospital mortalitytrends
spellingShingle Javier de Miguel-Díez
Ana Lopez-de-Andres
Rodrigo Jimenez-Garcia
Jose M. de Miguel-Yanes
Valentin Hernández-Barrera
David Carabantes-Alarcon
Jose J. Zamorano-Leon
Concepcion Noriega
National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020
Journal of Clinical Medicine
COPD
depression
sex
prevalence
in-hospital mortality
trends
title National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020
title_full National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020
title_fullStr National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020
title_full_unstemmed National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020
title_short National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020
title_sort national trends in prevalence of depression in men and women with chronic obstructive pulmonary disease hospitalized in spain 2016 2020
topic COPD
depression
sex
prevalence
in-hospital mortality
trends
url https://www.mdpi.com/2077-0383/11/21/6337
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