Adult diffuse hepatic hemangiomatosis
Diffuse hepatic hemangiomatosis (DHH) is an uncommon vascular lesion, though hemangiomas are the commonest benign tumors of the liver. The etiology is largely unknown to date; however, its association with giant cavernous hemangiomas (GCH) has been reported in the literature. We present herein, the...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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University of São Paulo
2022-09-01
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| Series: | Autopsy and Case Reports |
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| Online Access: | https://www.revistas.usp.br/autopsy/article/view/202822 |
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| author | Neha Bhardwaj Mayur Parkhi Manish Kumar Lileswar Kaman Suvradeep Mitra |
| author_facet | Neha Bhardwaj Mayur Parkhi Manish Kumar Lileswar Kaman Suvradeep Mitra |
| author_sort | Neha Bhardwaj |
| collection | DOAJ |
| description |
Diffuse hepatic hemangiomatosis (DHH) is an uncommon vascular lesion, though hemangiomas are the commonest benign tumors of the liver. The etiology is largely unknown to date; however, its association with giant cavernous hemangiomas (GCH) has been reported in the literature. We present herein, the case of a 37-year-old hypothyroid woman with abdominal fullness for 2 months. The contrast-enhanced computed tomography revealed multiple wellencapsulated lesions involving the liver lobes and was diagnosed as giant cavernous hemangiomas. Most of them, except the deep-seated ones, were enucleated. Histopathological examination highlighted the presence of GCH with irregular margin, replacement of hepatic parenchyma, and presence of multiple micro-hemangiomas suggesting the possibility of DHH further substantiated by retrospective radiological assessment. No extrahepatic vascular lesion was noted, and the post-operative recovery and follow-up were uneventful. Adult DHH is an uncommon entity. The diagnosis of DHH and its distinction from GCH are important from the management and prognostic point of view as recurrence, extrahepatic manifestations, features of consumption coagulopathy, and death from the complications are not uncommon.
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| first_indexed | 2024-12-10T12:56:28Z |
| format | Article |
| id | doaj.art-5b80da9bc92d4ac4874fda5a143ebded |
| institution | Directory Open Access Journal |
| issn | 2236-1960 |
| language | English |
| last_indexed | 2024-12-10T12:56:28Z |
| publishDate | 2022-09-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Autopsy and Case Reports |
| spelling | doaj.art-5b80da9bc92d4ac4874fda5a143ebded2022-12-22T01:48:04ZengUniversity of São PauloAutopsy and Case Reports2236-19602022-09-0112Adult diffuse hepatic hemangiomatosisNeha Bhardwaj0Mayur Parkhi1Manish Kumar2Lileswar Kaman3Suvradeep Mitra4Post Graduate Institute and Medical Education and Research (PGIMER), Department of Pathology, Chandigarh, IndiaPost Graduate Institute and Medical Education and Research (PGIMER), Department of Histopathology, Chandigarh, IndiaPost Graduate Institute and Medical Education and Research (PGIMER), Department of General Surgery, Chandigarh, IndiaPost Graduate Institute and Medical Education and Research (PGIMER), Department of General Surgery, Chandigarh, IndiaPost Graduate Institute and Medical Education and Research (PGIMER), Department of Histopathology, Chandigarh, India Diffuse hepatic hemangiomatosis (DHH) is an uncommon vascular lesion, though hemangiomas are the commonest benign tumors of the liver. The etiology is largely unknown to date; however, its association with giant cavernous hemangiomas (GCH) has been reported in the literature. We present herein, the case of a 37-year-old hypothyroid woman with abdominal fullness for 2 months. The contrast-enhanced computed tomography revealed multiple wellencapsulated lesions involving the liver lobes and was diagnosed as giant cavernous hemangiomas. Most of them, except the deep-seated ones, were enucleated. Histopathological examination highlighted the presence of GCH with irregular margin, replacement of hepatic parenchyma, and presence of multiple micro-hemangiomas suggesting the possibility of DHH further substantiated by retrospective radiological assessment. No extrahepatic vascular lesion was noted, and the post-operative recovery and follow-up were uneventful. Adult DHH is an uncommon entity. The diagnosis of DHH and its distinction from GCH are important from the management and prognostic point of view as recurrence, extrahepatic manifestations, features of consumption coagulopathy, and death from the complications are not uncommon. https://www.revistas.usp.br/autopsy/article/view/202822LiverVascular NeoplasmsHemangiomaCavernousPathology |
| spellingShingle | Neha Bhardwaj Mayur Parkhi Manish Kumar Lileswar Kaman Suvradeep Mitra Adult diffuse hepatic hemangiomatosis Autopsy and Case Reports Liver Vascular Neoplasms Hemangioma Cavernous Pathology |
| title | Adult diffuse hepatic hemangiomatosis |
| title_full | Adult diffuse hepatic hemangiomatosis |
| title_fullStr | Adult diffuse hepatic hemangiomatosis |
| title_full_unstemmed | Adult diffuse hepatic hemangiomatosis |
| title_short | Adult diffuse hepatic hemangiomatosis |
| title_sort | adult diffuse hepatic hemangiomatosis |
| topic | Liver Vascular Neoplasms Hemangioma Cavernous Pathology |
| url | https://www.revistas.usp.br/autopsy/article/view/202822 |
| work_keys_str_mv | AT nehabhardwaj adultdiffusehepatichemangiomatosis AT mayurparkhi adultdiffusehepatichemangiomatosis AT manishkumar adultdiffusehepatichemangiomatosis AT lileswarkaman adultdiffusehepatichemangiomatosis AT suvradeepmitra adultdiffusehepatichemangiomatosis |