From Birth to Weaning: A Window of Opportunity for Microbiota
(1) Background: The first 1000 days of life constitute a critical window of opportunity for microbiota development. Nutrients play a crucial role in enriching and diversifying the microbiota, derived not only from solid food but also from maternal dietary patterns during gestation. (2) Methods: We c...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/2/272 |
| _version_ | 1797339477234941952 |
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| author | Valentina Biagioli Greta Volpedo Antonella Riva Paolo Mainardi Pasquale Striano |
| author_facet | Valentina Biagioli Greta Volpedo Antonella Riva Paolo Mainardi Pasquale Striano |
| author_sort | Valentina Biagioli |
| collection | DOAJ |
| description | (1) Background: The first 1000 days of life constitute a critical window of opportunity for microbiota development. Nutrients play a crucial role in enriching and diversifying the microbiota, derived not only from solid food but also from maternal dietary patterns during gestation. (2) Methods: We conducted a comprehensive literature review using the PubMed database, covering eleven years (2013–2023). We included English-language reviews, original research papers, and meta-analyses, while excluding case reports and letters. (3) Results: Consensus in the literature emphasizes that our interaction with a multitude of microorganisms begins in the intrauterine environment and continues throughout our lives. The existing data suggest that early nutritional education programs, initiated during pregnancy and guiding infant diets during development, may influence the shaping of the gut microbiota, promoting long-term health. (4) Conclusions: Further research is necessary in the coming years to assess potential interventions and early nutritional models aimed at modulating the pediatric microbiota, especially in vulnerable populations such as premature newborns. |
| first_indexed | 2024-03-08T09:48:42Z |
| format | Article |
| id | doaj.art-5b820761ed314dd3a0cceab065b0b499 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-08T09:48:42Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-5b820761ed314dd3a0cceab065b0b4992024-01-29T14:10:08ZengMDPI AGNutrients2072-66432024-01-0116227210.3390/nu16020272From Birth to Weaning: A Window of Opportunity for MicrobiotaValentina Biagioli0Greta Volpedo1Antonella Riva2Paolo Mainardi3Pasquale Striano4Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16126 Genoa, ItalyDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16126 Genoa, ItalyDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16126 Genoa, ItalyDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16126 Genoa, ItalyDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16126 Genoa, Italy(1) Background: The first 1000 days of life constitute a critical window of opportunity for microbiota development. Nutrients play a crucial role in enriching and diversifying the microbiota, derived not only from solid food but also from maternal dietary patterns during gestation. (2) Methods: We conducted a comprehensive literature review using the PubMed database, covering eleven years (2013–2023). We included English-language reviews, original research papers, and meta-analyses, while excluding case reports and letters. (3) Results: Consensus in the literature emphasizes that our interaction with a multitude of microorganisms begins in the intrauterine environment and continues throughout our lives. The existing data suggest that early nutritional education programs, initiated during pregnancy and guiding infant diets during development, may influence the shaping of the gut microbiota, promoting long-term health. (4) Conclusions: Further research is necessary in the coming years to assess potential interventions and early nutritional models aimed at modulating the pediatric microbiota, especially in vulnerable populations such as premature newborns.https://www.mdpi.com/2072-6643/16/2/272microbiotahuman milk oligosaccharidescomplementary feedinggut–brain axisweaning |
| spellingShingle | Valentina Biagioli Greta Volpedo Antonella Riva Paolo Mainardi Pasquale Striano From Birth to Weaning: A Window of Opportunity for Microbiota Nutrients microbiota human milk oligosaccharides complementary feeding gut–brain axis weaning |
| title | From Birth to Weaning: A Window of Opportunity for Microbiota |
| title_full | From Birth to Weaning: A Window of Opportunity for Microbiota |
| title_fullStr | From Birth to Weaning: A Window of Opportunity for Microbiota |
| title_full_unstemmed | From Birth to Weaning: A Window of Opportunity for Microbiota |
| title_short | From Birth to Weaning: A Window of Opportunity for Microbiota |
| title_sort | from birth to weaning a window of opportunity for microbiota |
| topic | microbiota human milk oligosaccharides complementary feeding gut–brain axis weaning |
| url | https://www.mdpi.com/2072-6643/16/2/272 |
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