Enhancement of Human Immunodeficiency Virus-Specific CD8<sup>+</sup> T Cell Responses with TIGIT Blockade Involves Trogocytosis
Natural killer (NK) and CD8<sup>+</sup> T cell function is compromised in human immunodeficiency virus type 1 (HIV-1) infection by increased expression of inhibitory receptors such as TIGIT (T cell immunoreceptor with Ig and ITIM domains). Blocking inhibitory receptors or their ligands w...
Main Authors: | , , , |
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格式: | Article |
語言: | English |
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MDPI AG
2024-12-01
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叢編: | Pathogens |
主題: | |
在線閱讀: | https://www.mdpi.com/2076-0817/13/12/1137 |