Certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic options
Epilepsy is a common chronic neurological disease. The problems of people with epilepsy go well beyond epileptic seizures. Comorbidities in epilepsy are very common and often cause more problems to the patients than the seizures themselves. Although seizures are the most prominent clinical presentat...
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2021-08-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/6268 |
| _version_ | 1797841690926514176 |
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| author | N. V. Pizova A. V. Pizov |
| author_facet | N. V. Pizova A. V. Pizov |
| author_sort | N. V. Pizova |
| collection | DOAJ |
| description | Epilepsy is a common chronic neurological disease. The problems of people with epilepsy go well beyond epileptic seizures. Comorbidities in epilepsy are very common and often cause more problems to the patients than the seizures themselves. Although seizures are the most prominent clinical presentation of epilepsy, people with epilepsy are exposed to risk of not only seizures, but also of many health problems. Both children and adults with epilepsy often complain of memory impairment. It is commonly believed that cognitive dysfunction in epilepsy is multifactorial. The components that deteriorate cognitive functions include active seizures and especially generalized tonic-clonic seizures, traumatic brain injuries, structural epilepsy, and drug therapy. Cognitive dysfunction is very often present as far back as during the onset of epilepsy. The cognitive dysfunction detected in patients with epilepsy depend on the localization of the epileptic focus, the frequency and type of epileptic seizures, and changes in the interictal electroencephalogram. Seizures can be controlled with antiepileptic drugs in most patients with epilepsy. Therapy of cognitive dysfunction in patients with epilepsy presents significant difficulties, as there is no evidence of the efficacy of various drugs in cognitive disorders. The article presents a new Russian antiepileptic drug based on phenosanic acid as part of combination therapy in patients with partial epileptic seizures with or without secondary generalization, which can improve cognitive functions in patients with epilepsy. |
| first_indexed | 2024-04-09T16:35:24Z |
| format | Article |
| id | doaj.art-5b8de0d40c7d4022a61e3dd6a5844420 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:35:24Z |
| publishDate | 2021-08-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-5b8de0d40c7d4022a61e3dd6a58444202023-04-23T06:56:56ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902021-08-01010869310.21518/2079-701X-2021-10-86-935663Certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic optionsN. V. Pizova0A. V. Pizov1Yaroslavl State Medical UniversityYaroslavl State Pedagogical University named after K.D. UshinskyEpilepsy is a common chronic neurological disease. The problems of people with epilepsy go well beyond epileptic seizures. Comorbidities in epilepsy are very common and often cause more problems to the patients than the seizures themselves. Although seizures are the most prominent clinical presentation of epilepsy, people with epilepsy are exposed to risk of not only seizures, but also of many health problems. Both children and adults with epilepsy often complain of memory impairment. It is commonly believed that cognitive dysfunction in epilepsy is multifactorial. The components that deteriorate cognitive functions include active seizures and especially generalized tonic-clonic seizures, traumatic brain injuries, structural epilepsy, and drug therapy. Cognitive dysfunction is very often present as far back as during the onset of epilepsy. The cognitive dysfunction detected in patients with epilepsy depend on the localization of the epileptic focus, the frequency and type of epileptic seizures, and changes in the interictal electroencephalogram. Seizures can be controlled with antiepileptic drugs in most patients with epilepsy. Therapy of cognitive dysfunction in patients with epilepsy presents significant difficulties, as there is no evidence of the efficacy of various drugs in cognitive disorders. The article presents a new Russian antiepileptic drug based on phenosanic acid as part of combination therapy in patients with partial epileptic seizures with or without secondary generalization, which can improve cognitive functions in patients with epilepsy.https://www.med-sovet.pro/jour/article/view/6268epilepsycomorbiditiescognitive impairmenttherapyphenosanic acid |
| spellingShingle | N. V. Pizova A. V. Pizov Certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic options Медицинский совет epilepsy comorbidities cognitive impairment therapy phenosanic acid |
| title | Certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic options |
| title_full | Certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic options |
| title_fullStr | Certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic options |
| title_full_unstemmed | Certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic options |
| title_short | Certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic options |
| title_sort | certain risk factors for the development of cognitive impairment in persons with epilepsy and new therapeutic options |
| topic | epilepsy comorbidities cognitive impairment therapy phenosanic acid |
| url | https://www.med-sovet.pro/jour/article/view/6268 |
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