Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in Newborn

Most ofnewborns with Congenital Heart Defects (CHDs) can be detected by using echocardiography. However, if such defects are not diagnosed in earlier time, therefore a severe hypoxemia, shock, acidosis and death are considered of some potential sequelae. A prospective study from January 2012 to the...

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Main Authors: Aso Faeq Salih, Adnan Mohammed Hamawand, Riyadh Abd Aljabbar Sattar
Format: Article
Language:English
Published: Sulaimani Polytechnic University 2018-07-01
Series:Kurdistan Journal of Applied Research
Subjects:
Online Access:https://kjar.spu.edu.iq/index.php/kjar/article/view/212
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author Aso Faeq Salih
Adnan Mohammed Hamawand
Riyadh Abd Aljabbar Sattar
author_facet Aso Faeq Salih
Adnan Mohammed Hamawand
Riyadh Abd Aljabbar Sattar
author_sort Aso Faeq Salih
collection DOAJ
description Most ofnewborns with Congenital Heart Defects (CHDs) can be detected by using echocardiography. However, if such defects are not diagnosed in earlier time, therefore a severe hypoxemia, shock, acidosis and death are considered of some potential sequelae. A prospective study from January 2012 to the end of 2013 was performed and 2181 neonates were enrolled in the study. The pulse oximetry screening (POS) for both hands and one foot were obtained within the first 3-6 hours of life, when post ductal saturation was below 90%, it was considered as a positive screening, while when the saturation is between 90-95% and the difference between pre-and post-ductal saturation was more than 3%, the baby was provisionally considered to be screening as a positive then echocardiography is planned. Among 100 positive POS babies, 45 (45%) of them were detected with CHS, 12 (12%) was with a major CHS and 33 (33%) was with a minor CHS. Out of 12 patients with a major CHD 6 of them (50%) were asymptomatic at the time of POS.POS result was a true negative in 2078 patients, a true positive in 45 patients, false negative in 3 patients, and false positive in 55 and 28/55 of the false positive rate with POS had other pathology. The false positive rate with pulse oximetry screening is (55/2081) = 0.26%. Sensitivity, specificity, positive and negative predictive value for POS in detection of major CHD were 80%, 97.29%, 17.9% and 99.80%, respectively. Pulse oximetry screening is significantly improving the detection of life threatening congenital heart disease at an early stage.
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spelling doaj.art-5b8e874103c640a194a7e07334eed9252024-04-22T17:19:37ZengSulaimani Polytechnic UniversityKurdistan Journal of Applied Research2411-76842411-77062018-07-013210.24017/science.2018.2.22212Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in NewbornAso Faeq Salih0Adnan Mohammed Hamawand1Riyadh Abd Aljabbar Sattar2Pediatric Department, College of Medicine, University of Sulaimani, Sulaimani, IraqPediatric Department, College of Medicine, University of Sulaimani, Sulaimani, IraqPediatric Department, Pediatric Teaching Hospital, Ministry of Health, Sulaimani, IraqMost ofnewborns with Congenital Heart Defects (CHDs) can be detected by using echocardiography. However, if such defects are not diagnosed in earlier time, therefore a severe hypoxemia, shock, acidosis and death are considered of some potential sequelae. A prospective study from January 2012 to the end of 2013 was performed and 2181 neonates were enrolled in the study. The pulse oximetry screening (POS) for both hands and one foot were obtained within the first 3-6 hours of life, when post ductal saturation was below 90%, it was considered as a positive screening, while when the saturation is between 90-95% and the difference between pre-and post-ductal saturation was more than 3%, the baby was provisionally considered to be screening as a positive then echocardiography is planned. Among 100 positive POS babies, 45 (45%) of them were detected with CHS, 12 (12%) was with a major CHS and 33 (33%) was with a minor CHS. Out of 12 patients with a major CHD 6 of them (50%) were asymptomatic at the time of POS.POS result was a true negative in 2078 patients, a true positive in 45 patients, false negative in 3 patients, and false positive in 55 and 28/55 of the false positive rate with POS had other pathology. The false positive rate with pulse oximetry screening is (55/2081) = 0.26%. Sensitivity, specificity, positive and negative predictive value for POS in detection of major CHD were 80%, 97.29%, 17.9% and 99.80%, respectively. Pulse oximetry screening is significantly improving the detection of life threatening congenital heart disease at an early stage. https://kjar.spu.edu.iq/index.php/kjar/article/view/212Pediatrics, Pulse Oximetry, Congenital Heart Defects, Newborn.
spellingShingle Aso Faeq Salih
Adnan Mohammed Hamawand
Riyadh Abd Aljabbar Sattar
Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in Newborn
Kurdistan Journal of Applied Research
Pediatrics, Pulse Oximetry, Congenital Heart Defects, Newborn.
title Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in Newborn
title_full Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in Newborn
title_fullStr Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in Newborn
title_full_unstemmed Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in Newborn
title_short Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in Newborn
title_sort role of pulse oximetry screening for detection of life threatening congenital heart detects in newborn
topic Pediatrics, Pulse Oximetry, Congenital Heart Defects, Newborn.
url https://kjar.spu.edu.iq/index.php/kjar/article/view/212
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