Effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolism
Objective A rabbit model was used to evaluate the effects of bone-cemented hip arthroplasty on distal femoral blood flow and metabolism relative to that of the non-cemented contralateral leg. Methods The marrow cavity of the right hind femur was filled with bone cement. At each of the following time...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2018-12-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/0300060518802717 |
| _version_ | 1818920313890537472 |
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| author | Li-Cheng Xi Hong-Yu Li Ming Zhang Si-Cheng Huang |
| author_facet | Li-Cheng Xi Hong-Yu Li Ming Zhang Si-Cheng Huang |
| author_sort | Li-Cheng Xi |
| collection | DOAJ |
| description | Objective A rabbit model was used to evaluate the effects of bone-cemented hip arthroplasty on distal femoral blood flow and metabolism relative to that of the non-cemented contralateral leg. Methods The marrow cavity of the right hind femur was filled with bone cement. At each of the following time points, rabbits were randomly selected to receive an injection of one dose of 99m Tc-methylene diphosphonate and then immediately scanned using a gamma camera: immediately postoperatively and at 4 and 8 weeks postoperatively. A BL-410 model biofunction experimental system was used to analyze the acquired images and determine the radioactive counts of each hind leg. Results The X-ray and photographic images of the right femoral bones confirmed successful filling of the marrow cavity with bone cement. The radioactive counts were significantly lower in the experimental than control legs at each time point. The ratio of the radioactive count of the experimental to control leg increased considerably at each time point, but each ratio was <1. Conclusion Blocking the proximal femoral medullary cavity with bone cement was associated with significant lowering of the blood circulation of the femur and marrow, decreasing the distal femoral blood flow and bone metabolic rate. |
| first_indexed | 2024-12-20T01:19:46Z |
| format | Article |
| id | doaj.art-5b8eaa3f715b4248a8642bffa717295c |
| institution | Directory Open Access Journal |
| issn | 0300-0605 1473-2300 |
| language | English |
| last_indexed | 2024-12-20T01:19:46Z |
| publishDate | 2018-12-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-5b8eaa3f715b4248a8642bffa717295c2022-12-21T19:58:28ZengSAGE PublishingJournal of International Medical Research0300-06051473-23002018-12-014610.1177/0300060518802717Effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolismLi-Cheng XiHong-Yu LiMing ZhangSi-Cheng HuangObjective A rabbit model was used to evaluate the effects of bone-cemented hip arthroplasty on distal femoral blood flow and metabolism relative to that of the non-cemented contralateral leg. Methods The marrow cavity of the right hind femur was filled with bone cement. At each of the following time points, rabbits were randomly selected to receive an injection of one dose of 99m Tc-methylene diphosphonate and then immediately scanned using a gamma camera: immediately postoperatively and at 4 and 8 weeks postoperatively. A BL-410 model biofunction experimental system was used to analyze the acquired images and determine the radioactive counts of each hind leg. Results The X-ray and photographic images of the right femoral bones confirmed successful filling of the marrow cavity with bone cement. The radioactive counts were significantly lower in the experimental than control legs at each time point. The ratio of the radioactive count of the experimental to control leg increased considerably at each time point, but each ratio was <1. Conclusion Blocking the proximal femoral medullary cavity with bone cement was associated with significant lowering of the blood circulation of the femur and marrow, decreasing the distal femoral blood flow and bone metabolic rate.https://doi.org/10.1177/0300060518802717 |
| spellingShingle | Li-Cheng Xi Hong-Yu Li Ming Zhang Si-Cheng Huang Effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolism Journal of International Medical Research |
| title | Effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolism |
| title_full | Effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolism |
| title_fullStr | Effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolism |
| title_full_unstemmed | Effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolism |
| title_short | Effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolism |
| title_sort | effects of bone cement filling in rabbit proximal femoral medullary cavity on distal femoral blood flow and metabolism |
| url | https://doi.org/10.1177/0300060518802717 |
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