Systemic immune-inflammation index in twin pregnancies compared to singleton pregnancies
Objective To evaluate the systemic immune-inflammation index (SII) in twin pregnancies. Methods The retrospective study included 200 twin (dichorionic/ diamniotic and monochorionic/diamniotic) and 200 singleton pregnancies (control group). All pregnant women were in the first trimester (<14 weeks...
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Perinatal Medicine Foundation
2021-12-01
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| श्रृंखला: | Perinatal Journal |
| ऑनलाइन पहुंच: | https://perinataljournal.com/Archive/Article/20210293014 |
| _version_ | 1828016332653723648 |
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| author | Ezgi Turgut Bedri Sakcak Deniz Oluklu Şule Göncü Ayhan Dilek Şahin |
| author_facet | Ezgi Turgut Bedri Sakcak Deniz Oluklu Şule Göncü Ayhan Dilek Şahin |
| author_sort | Ezgi Turgut |
| collection | DOAJ |
| description | Objective To evaluate the systemic immune-inflammation index (SII) in twin pregnancies. Methods The retrospective study included 200 twin (dichorionic/ diamniotic and monochorionic/diamniotic) and 200 singleton pregnancies (control group). All pregnant women were in the first trimester (<14 weeks of gestation). The study and the control groups were compared in terms of demographic characteristics, laboratory test results, and SII values. Results The mean week of gestation was 9.7±2 in dichorionic diamniotic twin pregnancy group, 10.4±2 in monochorionic diamniotic twin pregnancy group and 9.4±2 for the control group (p=0.083). The lymphocyte value was lower in the dichorionic group and monochorionic group than in the control group (p=0.020 and p=0.020, respectively). The platelet-to-lymphocyte ratio (PLR) values were higher in the dichorionic group than in the control group (p=0.002). However, there was no statistical difference between the groups for neutrophil-to-lymphocyte ratio (NLR) and SII values (p>0.05). Conclusion Physiological inflammatory/immune reaction of early pregnancy may affect PLR values in twin pregnancies. We observed that chorionicity is considerable for these inflammatory indices, especially for dichorionic twin pregnancies. However, we could not detect a significant change in SII values in twin pregnancy. |
| first_indexed | 2024-04-10T10:32:00Z |
| format | Article |
| id | doaj.art-5b932f7d2ea446f48f62b51cbe04cff0 |
| institution | Directory Open Access Journal |
| issn | 1305-3124 |
| language | English |
| last_indexed | 2024-04-10T10:32:00Z |
| publishDate | 2021-12-01 |
| publisher | Perinatal Medicine Foundation |
| record_format | Article |
| series | Perinatal Journal |
| spelling | doaj.art-5b932f7d2ea446f48f62b51cbe04cff02023-02-15T16:21:03ZengPerinatal Medicine FoundationPerinatal Journal1305-31242021-12-0129325025410.2399/prn.21.0293014Systemic immune-inflammation index in twin pregnancies compared to singleton pregnanciesEzgi Turguthttps://orcid.org/0000-0002-5509-7888Bedri Sakcakhttps://orcid.org/0000-0003-0277-5072Deniz Olukluhttps://orcid.org/0000-0002-9050-2041Şule Göncü Ayhanhttps://orcid.org/0000-0002-5770-7555Dilek Şahinhttps://orcid.org/0000-0001-8567-9048Objective To evaluate the systemic immune-inflammation index (SII) in twin pregnancies. Methods The retrospective study included 200 twin (dichorionic/ diamniotic and monochorionic/diamniotic) and 200 singleton pregnancies (control group). All pregnant women were in the first trimester (<14 weeks of gestation). The study and the control groups were compared in terms of demographic characteristics, laboratory test results, and SII values. Results The mean week of gestation was 9.7±2 in dichorionic diamniotic twin pregnancy group, 10.4±2 in monochorionic diamniotic twin pregnancy group and 9.4±2 for the control group (p=0.083). The lymphocyte value was lower in the dichorionic group and monochorionic group than in the control group (p=0.020 and p=0.020, respectively). The platelet-to-lymphocyte ratio (PLR) values were higher in the dichorionic group than in the control group (p=0.002). However, there was no statistical difference between the groups for neutrophil-to-lymphocyte ratio (NLR) and SII values (p>0.05). Conclusion Physiological inflammatory/immune reaction of early pregnancy may affect PLR values in twin pregnancies. We observed that chorionicity is considerable for these inflammatory indices, especially for dichorionic twin pregnancies. However, we could not detect a significant change in SII values in twin pregnancy.https://perinataljournal.com/Archive/Article/20210293014 |
| spellingShingle | Ezgi Turgut Bedri Sakcak Deniz Oluklu Şule Göncü Ayhan Dilek Şahin Systemic immune-inflammation index in twin pregnancies compared to singleton pregnancies Perinatal Journal |
| title | Systemic immune-inflammation index in twin pregnancies compared to singleton pregnancies |
| title_full | Systemic immune-inflammation index in twin pregnancies compared to singleton pregnancies |
| title_fullStr | Systemic immune-inflammation index in twin pregnancies compared to singleton pregnancies |
| title_full_unstemmed | Systemic immune-inflammation index in twin pregnancies compared to singleton pregnancies |
| title_short | Systemic immune-inflammation index in twin pregnancies compared to singleton pregnancies |
| title_sort | systemic immune inflammation index in twin pregnancies compared to singleton pregnancies |
| url | https://perinataljournal.com/Archive/Article/20210293014 |
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