RNF213 Loss-of-Function Promotes Angiogenesis of Cerebral Microvascular Endothelial Cells in a Cellular State Dependent Manner

Enhanced and aberrant angiogenesis is one of the main features of Moyamoya disease (MMD) pathogenesis. The ring finger protein 213 (RNF213) and the variant p.R4810K have been linked with higher risks of MMD and intracranial arterial occlusion development in east Asian populations. The role of RNF213...

Полное описание

Библиографические подробности
Главные авторы: Vincent Roy, Alyssa Brodeur, Lydia Touzel Deschênes, Nicolas Dupré, François Gros-Louis
Формат: Статья
Язык:English
Опубликовано: MDPI AG 2022-12-01
Серии:Cells
Предметы:
Online-ссылка:https://www.mdpi.com/2073-4409/12/1/78