Role of YAP/TAZ in Cell Lineage Fate Determination and Related Signaling Pathways

Role of YAP/TAZ in Cell Lineage Fate Determination and Related Signaling Pathways

The penultimate effectors of the Hippo signaling pathways YAP and TAZ, are transcriptional co-activator proteins that play key roles in many diverse biological processes, ranging from cell proliferation, tumorigenesis, mechanosensing and cell lineage fate determination, to wound healing and regenera...

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Bibliographic Details
Main Authors: Boon C. Heng, Xuehui Zhang, Dominique Aubel, Yunyang Bai, Xiaochan Li, Yan Wei, Martin Fussenegger, Xuliang Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
differentiation
Hippo
signaling
stem cells
TAZ
YAP
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00735/full

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