Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospital
Abstract INTRODUCTION: The present study sought to assess the mean and activity based cost (ABC) of the laboratory diagnosis for tuberculosis through the application of conventional and molecular techniques-Xpert®MTB/RIF and Genotype®MTBDRplus-in a tertiary referral hospital in Brazil. METHODS:...
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Sociedade Brasileira de Medicina Tropical (SBMT)
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100301&lng=en&tlng=en |
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| author | Valéria Martins Soares Isabela Neves de Almeida Maria Cláudia Vater Suely Alves Lida Jouca de Assis Figueredo Luciene Scherer Afrânio Lineu Kritski Wânia da Silva Carvalho Silvana Spindola de Miranda |
| author_facet | Valéria Martins Soares Isabela Neves de Almeida Maria Cláudia Vater Suely Alves Lida Jouca de Assis Figueredo Luciene Scherer Afrânio Lineu Kritski Wânia da Silva Carvalho Silvana Spindola de Miranda |
| author_sort | Valéria Martins Soares |
| collection | DOAJ |
| description | Abstract INTRODUCTION: The present study sought to assess the mean and activity based cost (ABC) of the laboratory diagnosis for tuberculosis through the application of conventional and molecular techniques-Xpert®MTB/RIF and Genotype®MTBDRplus-in a tertiary referral hospital in Brazil. METHODS: The mean cost and ABC formed the basis for the cost analysis of the TB laboratory diagnosis. RESULTS: The mean cost and ABC were US$ 4.00 and US$ 3.24, respectively, for a bacilloscopy; US$ 6.73 and US$ 5.27 for a Lowenstein-Jensen (LJ) culture; US$ 105.42 and US$ 76.56 for a drug sensitivity test (DST)-proportions method (PM) in LJ; US$ 148.45 and US$ 136.80 for a DST-BACTECTM MGITTM 960 system; US$ 11.53 and US$ 9.89 for an Xpert®MTB/RIF; and US$ 84.21 and US$ 48.38 for a Genotype®MTBDRplus. CONCLUSIONS: The mean cost and ABC proved to be good decision-making parameters in the diagnosis of TB and MDR-TB. The effective implementation of algorithms will depend on the conditions at each location. |
| first_indexed | 2024-12-12T07:28:52Z |
| format | Article |
| id | doaj.art-5b99115ef055430e804b3c90e167f1e0 |
| institution | Directory Open Access Journal |
| issn | 0037-8682 1678-9849 |
| language | English |
| last_indexed | 2024-12-12T07:28:52Z |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-5b99115ef055430e804b3c90e167f1e02022-12-22T00:33:03ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical0037-86821678-98495310.1590/0037-8682-0175-2019S0037-86822020000100301Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospitalValéria Martins SoaresIsabela Neves de AlmeidaMaria Cláudia VaterSuely AlvesLida Jouca de Assis FigueredoLuciene SchererAfrânio Lineu KritskiWânia da Silva CarvalhoSilvana Spindola de MirandaAbstract INTRODUCTION: The present study sought to assess the mean and activity based cost (ABC) of the laboratory diagnosis for tuberculosis through the application of conventional and molecular techniques-Xpert®MTB/RIF and Genotype®MTBDRplus-in a tertiary referral hospital in Brazil. METHODS: The mean cost and ABC formed the basis for the cost analysis of the TB laboratory diagnosis. RESULTS: The mean cost and ABC were US$ 4.00 and US$ 3.24, respectively, for a bacilloscopy; US$ 6.73 and US$ 5.27 for a Lowenstein-Jensen (LJ) culture; US$ 105.42 and US$ 76.56 for a drug sensitivity test (DST)-proportions method (PM) in LJ; US$ 148.45 and US$ 136.80 for a DST-BACTECTM MGITTM 960 system; US$ 11.53 and US$ 9.89 for an Xpert®MTB/RIF; and US$ 84.21 and US$ 48.38 for a Genotype®MTBDRplus. CONCLUSIONS: The mean cost and ABC proved to be good decision-making parameters in the diagnosis of TB and MDR-TB. The effective implementation of algorithms will depend on the conditions at each location.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100301&lng=en&tlng=entuberculosismycobacteriadiagnosismean costactivity based cost |
| spellingShingle | Valéria Martins Soares Isabela Neves de Almeida Maria Cláudia Vater Suely Alves Lida Jouca de Assis Figueredo Luciene Scherer Afrânio Lineu Kritski Wânia da Silva Carvalho Silvana Spindola de Miranda Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospital Revista da Sociedade Brasileira de Medicina Tropical tuberculosis mycobacteria diagnosis mean cost activity based cost |
| title | Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospital |
| title_full | Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospital |
| title_fullStr | Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospital |
| title_full_unstemmed | Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospital |
| title_short | Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospital |
| title_sort | genotype r mtbdrplus and xpert r mtb rif in the diagnosis of tuberculosis and resistant tuberculosis cost analysis in a tertiary referral hospital |
| topic | tuberculosis mycobacteria diagnosis mean cost activity based cost |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100301&lng=en&tlng=en |
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