T cells and cancer: how metabolism shapes immunity.

T cells and cancer: how metabolism shapes immunity.

Tumour microenvironment is characterized by a consistent reduction in oxygen and blood-borne nutrients that significantly affects the metabolism of distinct cell subsets. Immune cells populating malignant lesions need to activate alternative pathways to overcome tumour-prolonged nutrient deprivation...

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Bibliographic Details
Main Authors:	Barbara eMolon, Bianca eCalì, Antonella eViola
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-02-01
Series:	Frontiers in Immunology
Subjects:	Immunotherapy Reactive Nitrogen Species Tumor Microenvironment immune escape T lymphocyte activation
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00020/full

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