Deposits of iron oxides in the human globus pallidus
Samples taken from the human brain (Globus Pallidus) have been investigated by physical techniques such as light microscopy, scanning electron microscopy, transmission electron microscopy, Mössbauer spectroscopy and SQUID magnetometry. SEM-EDX/TEM investigation reveals multielemental composition of...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2019-06-01
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| Series: | Open Physics |
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| Online Access: | https://doi.org/10.1515/phys-2019-0030 |
| _version_ | 1818730483956056064 |
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| author | Svobodová Helena Hlinková Jana Janega Pavol Kosnáč Daniel Filová Barbora Miglierini Marcel Dlháň Ľubor Ehrlich Hermann Valigura Dušan Boča Roman Polák Štefan Nagy Štefan Kopáni Martin |
| author_facet | Svobodová Helena Hlinková Jana Janega Pavol Kosnáč Daniel Filová Barbora Miglierini Marcel Dlháň Ľubor Ehrlich Hermann Valigura Dušan Boča Roman Polák Štefan Nagy Štefan Kopáni Martin |
| author_sort | Svobodová Helena |
| collection | DOAJ |
| description | Samples taken from the human brain (Globus Pallidus) have been investigated by physical techniques such as light microscopy, scanning electron microscopy, transmission electron microscopy, Mössbauer spectroscopy and SQUID magnetometry. SEM-EDX/TEM investigation reveals multielemental composition of hematite and magnetite nanocrystals with sizes ranging from 40 nm to 100 nm and hematite microcrystals from 3 μm to 7 μm. Room temperature Mössbauer spectra show quadrupole doublets assigning to hematite and ferrihydrite. SQUID measurements of temperature dependence of the mass magnetic susceptibility between T = 2 – 300 K at DC field B0 = 0.1 T, the field dependence of the mass magnetization taken at the fixed temperature T0 = 2.0 and 4.6 K and the zero-field cooled and field cooled magnetization experiments (ZFCM/FCM) confirm a presence of ferrimagnetic phases such as maghemite and/or magnetite with hysteresis loops surviving until the room temperature. Differences between these measurements from the point of view of iron oxides detected can indicate important processes in human brain and interactions between ferritin as a physiological source of iron and surrounding environment. |
| first_indexed | 2024-12-17T23:02:30Z |
| format | Article |
| id | doaj.art-5b9ab382fb97476398fa88f583470e94 |
| institution | Directory Open Access Journal |
| issn | 2391-5471 |
| language | English |
| last_indexed | 2024-12-17T23:02:30Z |
| publishDate | 2019-06-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Physics |
| spelling | doaj.art-5b9ab382fb97476398fa88f583470e942022-12-21T21:29:22ZengDe GruyterOpen Physics2391-54712019-06-0117129129810.1515/phys-2019-0030phys-2019-0030Deposits of iron oxides in the human globus pallidusSvobodová Helena0Hlinková Jana1Janega Pavol2Kosnáč Daniel3Filová Barbora4Miglierini Marcel5Dlháň Ľubor6Ehrlich Hermann7Valigura Dušan8Boča Roman9Polák Štefan10Nagy Štefan11Kopáni Martin12Institute of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University, 813 72Bratislava, SlovakiaInstitute of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University, 813 72Bratislava, SlovakiaInstitute of Pathological Anatomy, Faculty of Medicine, Comenius University, Bratislava, SlovakiaInstitute of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University, 813 72Bratislava, SlovakiaInstitute of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University, 813 72Bratislava, SlovakiaSlovak University of Technology, FEI and FCHPT, Bratislava, SlovakiaSlovak University of Technology, FEI and FCHPT, Bratislava, SlovakiaInstitute of Experimental Physics, TU Bergakademie Freiberg, Freiberg, GermanyDepartment of Chemistry, Faculty of Natural Sciences, University of SS Cyril and Methodius, Trnava, SlovakiaDepartment of Chemistry, Faculty of Natural Sciences, University of SS Cyril and Methodius, Trnava, SlovakiaInstitute of Histology and Embryology, Faculty of Medicine, Comenius University, Bratislava, SlovakiaInstitute of Materials and Machine Mechanics, Slovak Academy of Sciences, Bratislava, SlovakiaInstitute of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University, 813 72Bratislava, SlovakiaSamples taken from the human brain (Globus Pallidus) have been investigated by physical techniques such as light microscopy, scanning electron microscopy, transmission electron microscopy, Mössbauer spectroscopy and SQUID magnetometry. SEM-EDX/TEM investigation reveals multielemental composition of hematite and magnetite nanocrystals with sizes ranging from 40 nm to 100 nm and hematite microcrystals from 3 μm to 7 μm. Room temperature Mössbauer spectra show quadrupole doublets assigning to hematite and ferrihydrite. SQUID measurements of temperature dependence of the mass magnetic susceptibility between T = 2 – 300 K at DC field B0 = 0.1 T, the field dependence of the mass magnetization taken at the fixed temperature T0 = 2.0 and 4.6 K and the zero-field cooled and field cooled magnetization experiments (ZFCM/FCM) confirm a presence of ferrimagnetic phases such as maghemite and/or magnetite with hysteresis loops surviving until the room temperature. Differences between these measurements from the point of view of iron oxides detected can indicate important processes in human brain and interactions between ferritin as a physiological source of iron and surrounding environment.https://doi.org/10.1515/phys-2019-0030human globus pallidusiron oxidesmössbauer spectroscopysquid magnetometry87.64.pj76.30.fc07.55.ge |
| spellingShingle | Svobodová Helena Hlinková Jana Janega Pavol Kosnáč Daniel Filová Barbora Miglierini Marcel Dlháň Ľubor Ehrlich Hermann Valigura Dušan Boča Roman Polák Štefan Nagy Štefan Kopáni Martin Deposits of iron oxides in the human globus pallidus Open Physics human globus pallidus iron oxides mössbauer spectroscopy squid magnetometry 87.64.pj 76.30.fc 07.55.ge |
| title | Deposits of iron oxides in the human globus pallidus |
| title_full | Deposits of iron oxides in the human globus pallidus |
| title_fullStr | Deposits of iron oxides in the human globus pallidus |
| title_full_unstemmed | Deposits of iron oxides in the human globus pallidus |
| title_short | Deposits of iron oxides in the human globus pallidus |
| title_sort | deposits of iron oxides in the human globus pallidus |
| topic | human globus pallidus iron oxides mössbauer spectroscopy squid magnetometry 87.64.pj 76.30.fc 07.55.ge |
| url | https://doi.org/10.1515/phys-2019-0030 |
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