Case Report of an Injectional Anthrax in France, 2012

(1) Background: <i>Bacillus anthracis</i> is a spore-forming, Gram-positive bacterium causing anthrax, a zoonosis affecting mainly livestock. When occasionally infecting humans, <i>B. anthracis</i> provokes three different clinical forms: cutaneous, digestive and inhalational...

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Bibliographic Details
Main Authors: Jean-Marc Thouret, Olivier Rogeaux, Emmanuel Beaudouin, Marion Levast, Vincent Ramisse, Fabrice V. Biot, Eric Valade, François Thibault, Olivier Gorgé, Jean-Nicolas Tournier
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/8/7/985
Description
Summary:(1) Background: <i>Bacillus anthracis</i> is a spore-forming, Gram-positive bacterium causing anthrax, a zoonosis affecting mainly livestock. When occasionally infecting humans, <i>B. anthracis</i> provokes three different clinical forms: cutaneous, digestive and inhalational anthrax. More recently, an injectional anthrax form has been described in intravenous drug users. (2) Case presentation: We report here the clinical and microbiological features, as well as the strain phylogenetic analysis, of the only injectional anthrax case observed in France so far. A 27-year-old patient presented a massive dermohypodermatitis with an extensive edema of the right arm, and the development of drug-resistant shocks. After three weeks in an intensive care unit, the patient recovered, but the microbiological identification of <i>B. anthracis</i> was achieved after a long delay. (3) Conclusions: Anthrax diagnostic may be difficult clinically and microbiologically. The phylogenetic analysis of the <i>Bacillus anthracis</i> strain PF1 confirmed its relatedness to the injectional anthrax European outbreak group-II.
ISSN:2076-2607