Structure Prediction and Genome Mining‐Aided Discovery of the Bacterial C‐Terminal Tryptophan Prenyltransferase PalQ

Structure Prediction and Genome Mining‐Aided Discovery of the Bacterial C‐Terminal Tryptophan Prenyltransferase PalQ

Abstract Post‐translational prenylations, found in eukaryotic primary metabolites and bacterial secondary metabolites, play crucial roles in biomolecular interactions. Employing genome mining methods combined with AlphaFold2‐based predictions of protein interactions, PalQ , a prenyltransferase respo...

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Bibliographic Details
Main Authors: Azusa Miyata, Sohei Ito, Daisuke Fujinami
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
genome mining
post‐translational modification
prenylation
structure prediction
Online Access:https://doi.org/10.1002/advs.202307372

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