miR-214-3p-Sufu-GLI1 is a novel regulatory axis controlling inflammatory smooth muscle cell differentiation from stem cells and neointimal hyperplasia

miR-214-3p-Sufu-GLI1 is a novel regulatory axis controlling inflammatory smooth muscle cell differentiation from stem cells and neointimal hyperplasia

Abstract Background Inflammatory smooth muscle cells (iSMCs) generated from adventitial stem/progenitor cells (AdSPCs) have been recognised as a new player in cardiovascular disease, and microRNA-214-3p (miR-214-3p) has been implicated in mature vascular SMC functions and neointimal hyperplasia. Her...

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Bibliographic Details
Main Authors:	Shiping He, Feng Yang, Mei Yang, Weiwei An, Eithne Margaret Maguire, Qishan Chen, Rui Xiao, Wei Wu, Li Zhang, Wen Wang, Qingzhong Xiao
Format:	Article
Language:	English
Published:	BMC 2020-11-01
Series:	Stem Cell Research & Therapy
Subjects:	Adventitia stem/progenitor cells Neointima formation Inflammatory smooth muscle cell Smooth muscle cell differentiation MicroRNA-214 MicroRNAs
Online Access:	http://link.springer.com/article/10.1186/s13287-020-01989-w

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