Cost-effectiveness of chronic hepatitis C screening and treatment
Hepatitis C virus (HCV) infection is the second most common cause of chronic liver disease in South Korea, with a prevalence ranging from 0.6% to 0.8%, and HCV infection incidence increases with age. The anti-HCV antibody test, which is cheaper than the HCV RNA assay, is widely used to screen for HC...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Association for the Study of the Liver
2022-04-01
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| Series: | Clinical and Molecular Hepatology |
| Subjects: | |
| Online Access: | http://e-cmh.org/upload/pdf/cmh-2021-0193.pdf |
| _version_ | 1811329829862113280 |
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| author | Hye Won Lee Hankil Lee Beom Kyung Kim Young Chang Jae Young Jang Do Young Kim |
| author_facet | Hye Won Lee Hankil Lee Beom Kyung Kim Young Chang Jae Young Jang Do Young Kim |
| author_sort | Hye Won Lee |
| collection | DOAJ |
| description | Hepatitis C virus (HCV) infection is the second most common cause of chronic liver disease in South Korea, with a prevalence ranging from 0.6% to 0.8%, and HCV infection incidence increases with age. The anti-HCV antibody test, which is cheaper than the HCV RNA assay, is widely used to screen for HCV infections; however, the underdiagnosis of HCV is a major barrier to the elimination of HCV infections. Although several risk factors have been associated with HCV infections, including intravenous drug use, blood transfusions, and hemodialysis, most patients with HCV infections present with no identifiable risk factors. Universal screening for HCV in adults has been suggested to improve the detection of HCV infections. We reviewed the cost-effectiveness of HCV screening and the methodologies used to perform screening. Recent studies have suggested that universal HCV screening and treatment using direct-acting antivirals represent cost-effective approaches to the prevention and treatment of HCV infection. However, the optimal timing and frequency of HCV screening remain unclear, and further studies are necessary to determine the best approaches for the elimination of HCV infections. |
| first_indexed | 2024-04-13T15:50:50Z |
| format | Article |
| id | doaj.art-5ba4bd0ea2744d1587571cd15dc29a01 |
| institution | Directory Open Access Journal |
| issn | 2287-2728 2287-285X |
| language | English |
| last_indexed | 2024-04-13T15:50:50Z |
| publishDate | 2022-04-01 |
| publisher | Korean Association for the Study of the Liver |
| record_format | Article |
| series | Clinical and Molecular Hepatology |
| spelling | doaj.art-5ba4bd0ea2744d1587571cd15dc29a012022-12-22T02:40:51ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2022-04-0128216417310.3350/cmh.2021.01931652Cost-effectiveness of chronic hepatitis C screening and treatmentHye Won Lee0Hankil Lee1Beom Kyung Kim2Young Chang3Jae Young Jang4Do Young Kim5 Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea College of Pharmacy, Ajou University, Suwon, Korea Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Internal Medicine, Digestive Disease Center, Institute for Digestive Research, Soonchunhyang University College of Medicine, Seoul, Korea Department of Internal Medicine, Digestive Disease Center, Institute for Digestive Research, Soonchunhyang University College of Medicine, Seoul, Korea Department of Internal Medicine, Yonsei University College of Medicine, Seoul, KoreaHepatitis C virus (HCV) infection is the second most common cause of chronic liver disease in South Korea, with a prevalence ranging from 0.6% to 0.8%, and HCV infection incidence increases with age. The anti-HCV antibody test, which is cheaper than the HCV RNA assay, is widely used to screen for HCV infections; however, the underdiagnosis of HCV is a major barrier to the elimination of HCV infections. Although several risk factors have been associated with HCV infections, including intravenous drug use, blood transfusions, and hemodialysis, most patients with HCV infections present with no identifiable risk factors. Universal screening for HCV in adults has been suggested to improve the detection of HCV infections. We reviewed the cost-effectiveness of HCV screening and the methodologies used to perform screening. Recent studies have suggested that universal HCV screening and treatment using direct-acting antivirals represent cost-effective approaches to the prevention and treatment of HCV infection. However, the optimal timing and frequency of HCV screening remain unclear, and further studies are necessary to determine the best approaches for the elimination of HCV infections.http://e-cmh.org/upload/pdf/cmh-2021-0193.pdfcost-effectivenesshepatitis cscreening |
| spellingShingle | Hye Won Lee Hankil Lee Beom Kyung Kim Young Chang Jae Young Jang Do Young Kim Cost-effectiveness of chronic hepatitis C screening and treatment Clinical and Molecular Hepatology cost-effectiveness hepatitis c screening |
| title | Cost-effectiveness of chronic hepatitis C screening and treatment |
| title_full | Cost-effectiveness of chronic hepatitis C screening and treatment |
| title_fullStr | Cost-effectiveness of chronic hepatitis C screening and treatment |
| title_full_unstemmed | Cost-effectiveness of chronic hepatitis C screening and treatment |
| title_short | Cost-effectiveness of chronic hepatitis C screening and treatment |
| title_sort | cost effectiveness of chronic hepatitis c screening and treatment |
| topic | cost-effectiveness hepatitis c screening |
| url | http://e-cmh.org/upload/pdf/cmh-2021-0193.pdf |
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