Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocol

Comparative pharmacoeconomic analysis of treatment according to ALL-MB-2002 protocol between two groups of children with acute lymphoblastic leukemia (ALL) (n=53) depending on use of intravenous immunoglobulin (IVIG) aiming to infectious complications preventing was conducted. It is shown, that actu...

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Main Authors: N. V. Miga, A. S. Shmargun, O. V. Aleinikova
Format: Article
Language:Russian
Published: ABV-press 2022-11-01
Series:Онкогематология
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/774
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author N. V. Miga
A. S. Shmargun
O. V. Aleinikova
author_facet N. V. Miga
A. S. Shmargun
O. V. Aleinikova
author_sort N. V. Miga
collection DOAJ
description Comparative pharmacoeconomic analysis of treatment according to ALL-MB-2002 protocol between two groups of children with acute lymphoblastic leukemia (ALL) (n=53) depending on use of intravenous immunoglobulin (IVIG) aiming to infectious complications preventing was conducted. It is shown, that actual protocol cost in group of children treating with IVIG in 1,5 times low (р<0,001). Price reduction of medicamentous treatment in this group of patients occur due to reduction of complications treatment cost, p<0,001. Decreasing time of treatment interruptions in group of patients with IVIG result in severe reduction of hospitalization cost (p<0,001). Application of this drug is more economic because of almost in 2 times reduction cost/efficiency ratio and 1,4 times increasing of additional years of life in ALL patients.
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spelling doaj.art-5ba688ca515f405ab13fa11c2b2627aa2023-03-30T20:15:16ZrusABV-pressОнкогематология1818-83462413-40232022-11-0103283410.17650/1818-8346-2009-0-3-28-34652Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocolN. V. Miga0A. S. Shmargun1O. V. Aleinikova2Republic Centre for Paediatric Oncology and HaematologyRepublic Centre for Paediatric Oncology and HaematologyRepublic Centre for Paediatric Oncology and HaematologyComparative pharmacoeconomic analysis of treatment according to ALL-MB-2002 protocol between two groups of children with acute lymphoblastic leukemia (ALL) (n=53) depending on use of intravenous immunoglobulin (IVIG) aiming to infectious complications preventing was conducted. It is shown, that actual protocol cost in group of children treating with IVIG in 1,5 times low (р<0,001). Price reduction of medicamentous treatment in this group of patients occur due to reduction of complications treatment cost, p<0,001. Decreasing time of treatment interruptions in group of patients with IVIG result in severe reduction of hospitalization cost (p<0,001). Application of this drug is more economic because of almost in 2 times reduction cost/efficiency ratio and 1,4 times increasing of additional years of life in ALL patients.https://oncohematology.abvpress.ru/ongm/article/view/774childrenacute lymphoblastic leukemiapharmacoeconomic analysisintravenous immunoglobulin
spellingShingle N. V. Miga
A. S. Shmargun
O. V. Aleinikova
Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocol
Онкогематология
children
acute lymphoblastic leukemia
pharmacoeconomic analysis
intravenous immunoglobulin
title Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocol
title_full Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocol
title_fullStr Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocol
title_full_unstemmed Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocol
title_short Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocol
title_sort pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to all mb 2002 protocol
topic children
acute lymphoblastic leukemia
pharmacoeconomic analysis
intravenous immunoglobulin
url https://oncohematology.abvpress.ru/ongm/article/view/774
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AT asshmargun pharmacoeconomicanalysisoftreatmentofchildrenwithacutelymphoblasticleukemiaaccordingtoallmb2002protocol
AT ovaleinikova pharmacoeconomicanalysisoftreatmentofchildrenwithacutelymphoblasticleukemiaaccordingtoallmb2002protocol