Comprehensive review of safety in Experimental Human Pneumococcal Challenge.

Comprehensive review of safety in Experimental Human Pneumococcal Challenge.

<h4>Introduction</h4>Experimental Human Pneumococcal Challenge (EHPC) involves the controlled exposure of adults to a specific antibiotic-sensitive Streptococcus pneumoniae serotype, to induce nasopharyngeal colonisation for the purpose of vaccine research. The aims are to review compreh...

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Main Authors: Ryan E Robinson, Christopher Myerscough, Nengjie He, Helen Hill, Wendi A Shepherd, Patricia Gonzalez-Dias, Konstantinos Liatsikos, Samuel Latham, Fred Fyles, Klara Doherty, Phoebe Hazenberg, Fathimath Shiham, Daniella Mclenghan, Hugh Adler, Vicki Randles, Seher Zaidi, Angela Hyder-Wright, Elena Mitsi, Hassan Burhan, Ben Morton, Jamie Rylance, Maia Lesosky, Stephen B Gordon, Andrea M Collins, Daniela M Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0284399

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