Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
Ginseng, a medicinal plant of the genus <i>Panax</i>, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming...
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MDPI AG
2023-05-01
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Online Access: | https://www.mdpi.com/1420-3049/28/9/3863 |
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author | Jose Antonio Valdés-González Marta Sánchez Ignacio Moratilla-Rivera Irene Iglesias María Pilar Gómez-Serranillos |
author_facet | Jose Antonio Valdés-González Marta Sánchez Ignacio Moratilla-Rivera Irene Iglesias María Pilar Gómez-Serranillos |
author_sort | Jose Antonio Valdés-González |
collection | DOAJ |
description | Ginseng, a medicinal plant of the genus <i>Panax</i>, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popular as a remedy for fatigue and asthenia. This review provides an update on current research pertaining to ginseng and its isolated compounds, namely, ginsenosides and polysaccharides. The primary focus is on three crucial pharmacological activities, namely, immunomodulation, anti-inflammatory, and anti-cancer effects. The review encompasses studies on both isolated compounds and various ginseng extracts obtained from the root, leaves, and berries. |
first_indexed | 2024-03-11T04:12:07Z |
format | Article |
id | doaj.art-5ba9d31fd1cb48819cecaec1d724f057 |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-03-11T04:12:07Z |
publishDate | 2023-05-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-5ba9d31fd1cb48819cecaec1d724f0572023-11-17T23:24:28ZengMDPI AGMolecules1420-30492023-05-01289386310.3390/molecules28093863Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological UpdateJose Antonio Valdés-González0Marta Sánchez1Ignacio Moratilla-Rivera2Irene Iglesias3María Pilar Gómez-Serranillos4Departamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainGinseng, a medicinal plant of the genus <i>Panax</i>, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popular as a remedy for fatigue and asthenia. This review provides an update on current research pertaining to ginseng and its isolated compounds, namely, ginsenosides and polysaccharides. The primary focus is on three crucial pharmacological activities, namely, immunomodulation, anti-inflammatory, and anti-cancer effects. The review encompasses studies on both isolated compounds and various ginseng extracts obtained from the root, leaves, and berries.https://www.mdpi.com/1420-3049/28/9/3863ginsenosidesginsengimmunomodulationanti-inflammatoryanti-cancersaponins |
spellingShingle | Jose Antonio Valdés-González Marta Sánchez Ignacio Moratilla-Rivera Irene Iglesias María Pilar Gómez-Serranillos Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update Molecules ginsenosides ginseng immunomodulation anti-inflammatory anti-cancer saponins |
title | Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update |
title_full | Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update |
title_fullStr | Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update |
title_full_unstemmed | Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update |
title_short | Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update |
title_sort | immunomodulatory anti inflammatory and anti cancer properties of ginseng a pharmacological update |
topic | ginsenosides ginseng immunomodulation anti-inflammatory anti-cancer saponins |
url | https://www.mdpi.com/1420-3049/28/9/3863 |
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