Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update

Ginseng, a medicinal plant of the genus <i>Panax</i>, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming...

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Main Authors: Jose Antonio Valdés-González, Marta Sánchez, Ignacio Moratilla-Rivera, Irene Iglesias, María Pilar Gómez-Serranillos
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/9/3863
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author Jose Antonio Valdés-González
Marta Sánchez
Ignacio Moratilla-Rivera
Irene Iglesias
María Pilar Gómez-Serranillos
author_facet Jose Antonio Valdés-González
Marta Sánchez
Ignacio Moratilla-Rivera
Irene Iglesias
María Pilar Gómez-Serranillos
author_sort Jose Antonio Valdés-González
collection DOAJ
description Ginseng, a medicinal plant of the genus <i>Panax</i>, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popular as a remedy for fatigue and asthenia. This review provides an update on current research pertaining to ginseng and its isolated compounds, namely, ginsenosides and polysaccharides. The primary focus is on three crucial pharmacological activities, namely, immunomodulation, anti-inflammatory, and anti-cancer effects. The review encompasses studies on both isolated compounds and various ginseng extracts obtained from the root, leaves, and berries.
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spelling doaj.art-5ba9d31fd1cb48819cecaec1d724f0572023-11-17T23:24:28ZengMDPI AGMolecules1420-30492023-05-01289386310.3390/molecules28093863Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological UpdateJose Antonio Valdés-González0Marta Sánchez1Ignacio Moratilla-Rivera2Irene Iglesias3María Pilar Gómez-Serranillos4Departamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, SpainGinseng, a medicinal plant of the genus <i>Panax</i>, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popular as a remedy for fatigue and asthenia. This review provides an update on current research pertaining to ginseng and its isolated compounds, namely, ginsenosides and polysaccharides. The primary focus is on three crucial pharmacological activities, namely, immunomodulation, anti-inflammatory, and anti-cancer effects. The review encompasses studies on both isolated compounds and various ginseng extracts obtained from the root, leaves, and berries.https://www.mdpi.com/1420-3049/28/9/3863ginsenosidesginsengimmunomodulationanti-inflammatoryanti-cancersaponins
spellingShingle Jose Antonio Valdés-González
Marta Sánchez
Ignacio Moratilla-Rivera
Irene Iglesias
María Pilar Gómez-Serranillos
Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
Molecules
ginsenosides
ginseng
immunomodulation
anti-inflammatory
anti-cancer
saponins
title Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_full Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_fullStr Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_full_unstemmed Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_short Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_sort immunomodulatory anti inflammatory and anti cancer properties of ginseng a pharmacological update
topic ginsenosides
ginseng
immunomodulation
anti-inflammatory
anti-cancer
saponins
url https://www.mdpi.com/1420-3049/28/9/3863
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