Assembly of infectious Kaposi’s sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer

Assembly of infectious Kaposi’s sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer

Herpesviruses cause severe diseases particularly in immunocompromised patients. Both genome packaging and release from the capsid require a unique portal channel occupying one of the 12 capsid vertices. Here, we report the 2.6 Å crystal structure of the pentameric pORF19 of the γ-herpesvirus Kaposi’...

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Bibliographic Details
Main Authors: Peter Naniima, Eleonora Naimo, Sandra Koch, Ute Curth, Khaled R. Alkharsah, Luisa J. Ströh, Anne Binz, Jan-Marc Beneke, Benjamin Vollmer, Heike Böning, Eva Maria Borst, Prashant Desai, Jens Bohne, Martin Messerle, Rudolf Bauerfeind, Pierre Legrand, Beate Sodeik, Thomas F. Schulz, Thomas Krey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568140/?tool=EBI

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