A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement

A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement

Abstract Background Microelectrode array (MEA) systems are valuable for in vitro assessment of neurotoxicity and drug efficiency. However, several difficulties such as protracted functional maturation and high experimental costs hinder the use of MEA analysis requiring human induced pluripotent stem...

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Bibliographic Details
Main Authors: Xiaobo Han, Naoki Matsuda, Yuto Ishibashi, Aoi Odawara, Sayuri Takahashi, Norie Tooi, Koshi Kinoshita, Ikuro Suzuki
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-12-01
Series:Biomaterials Research
Subjects:
SCAD device
Microelectrodes array
Convenient application
Human induced pluripotent stem cells
Peripheral neurons
Neural network function
Online Access:https://doi.org/10.1186/s40824-022-00324-z

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