Effects of Periconceptional Multivitamin Supplementation on Folate and Homocysteine Levels Depending on Genetic Variants of Methyltetrahydrofolate Reductase in Infertile Japanese Women

Effects of Periconceptional Multivitamin Supplementation on Folate and Homocysteine Levels Depending on Genetic Variants of Methyltetrahydrofolate Reductase in Infertile Japanese Women

Methylenetetrahydrofolate reductase (MTHFR) has various polymorphisms, and the effects of periconceptional folic acid supplementation for decreasing neural tube defects (NTDs) risk differ depending on the genotypes. This study analyzed the effectiveness of multivitamin supplementation on folate insu...

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Bibliographic Details
Main Authors: Keiji Kuroda, Takashi Horikawa, Yoko Gekka, Azusa Moriyama, Kazuki Nakao, Hiroyasu Juen, Satoru Takamizawa, Yuko Ojiro, Koji Nakagawa, Rikikazu Sugiyama
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Nutrients
Subjects:
folic acid
homocysteine
infertility
methyltetrahydrofolate reductase (MTHFR)
multivitamin supplementation
Vitamin D
Online Access:https://www.mdpi.com/2072-6643/13/4/1381

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