Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 Puzzle
Although the precise pathogenesis of coronavirus disease 2019 (COVID-19) currently remains unknown, its complex nature is gradually being revealed. COVID-19 is a disease caused by the SARS-CoV-2 virus and leads to respiratory dysfunction. Studies on hemostatic parameters have showed that COVID-19 si...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/3/370 |
| _version_ | 1797540752858808320 |
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| author | Magdalena Ulanowska Beata Olas |
| author_facet | Magdalena Ulanowska Beata Olas |
| author_sort | Magdalena Ulanowska |
| collection | DOAJ |
| description | Although the precise pathogenesis of coronavirus disease 2019 (COVID-19) currently remains unknown, its complex nature is gradually being revealed. COVID-19 is a disease caused by the SARS-CoV-2 virus and leads to respiratory dysfunction. Studies on hemostatic parameters have showed that COVID-19 significantly affects the disruption of the coagulation system and may contribute to coagulation and thrombotic events. A relevant cause of hemostasis disorders is inflammation and cytokine storms, which cause, for example, endothelial dysfunction in blood vessels. In order to prevent and treat states of hypercoagulability and thrombosis, the administration of anticoagulants, e.g., heparin, is recommended. The present mini-review describes the relationship between hemostasis and COVID-19, and discusses whether this relationship may cast light on the nature of COVID-19. The present short manuscript also examines the relationship between blood platelets and COVID-19. In addition, the paper explores the potential use of antiplatelet drugs in COVID-19 cases. The studies were identified by searching electronic databases, including PubMed and SCOPUS. |
| first_indexed | 2024-03-10T13:05:45Z |
| format | Article |
| id | doaj.art-5bb595deaea346f888303d68ed265dce |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T13:05:45Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-5bb595deaea346f888303d68ed265dce2023-11-21T11:09:16ZengMDPI AGPathogens2076-08172021-03-0110337010.3390/pathogens10030370Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 PuzzleMagdalena Ulanowska0Beata Olas1Department of General Biochemistry, University of Lodz, Pomorska 141/3, 90-236 Lodz, PolandDepartment of General Biochemistry, University of Lodz, Pomorska 141/3, 90-236 Lodz, PolandAlthough the precise pathogenesis of coronavirus disease 2019 (COVID-19) currently remains unknown, its complex nature is gradually being revealed. COVID-19 is a disease caused by the SARS-CoV-2 virus and leads to respiratory dysfunction. Studies on hemostatic parameters have showed that COVID-19 significantly affects the disruption of the coagulation system and may contribute to coagulation and thrombotic events. A relevant cause of hemostasis disorders is inflammation and cytokine storms, which cause, for example, endothelial dysfunction in blood vessels. In order to prevent and treat states of hypercoagulability and thrombosis, the administration of anticoagulants, e.g., heparin, is recommended. The present mini-review describes the relationship between hemostasis and COVID-19, and discusses whether this relationship may cast light on the nature of COVID-19. The present short manuscript also examines the relationship between blood platelets and COVID-19. In addition, the paper explores the potential use of antiplatelet drugs in COVID-19 cases. The studies were identified by searching electronic databases, including PubMed and SCOPUS.https://www.mdpi.com/2076-0817/10/3/370COVID-19cardiovascular diseasehemostasis |
| spellingShingle | Magdalena Ulanowska Beata Olas Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 Puzzle Pathogens COVID-19 cardiovascular disease hemostasis |
| title | Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 Puzzle |
| title_full | Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 Puzzle |
| title_fullStr | Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 Puzzle |
| title_full_unstemmed | Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 Puzzle |
| title_short | Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 Puzzle |
| title_sort | modulation of hemostasis in covid 19 blood platelets may be important pieces in the covid 19 puzzle |
| topic | COVID-19 cardiovascular disease hemostasis |
| url | https://www.mdpi.com/2076-0817/10/3/370 |
| work_keys_str_mv | AT magdalenaulanowska modulationofhemostasisincovid19bloodplateletsmaybeimportantpiecesinthecovid19puzzle AT beataolas modulationofhemostasisincovid19bloodplateletsmaybeimportantpiecesinthecovid19puzzle |