Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles?
Objective: To investigate the effect of laser-assisted hatching (LAH) compared with mechanical-assisted hatching (MAH) for enhancing clinical outcomes in frozen-thawed blastocysts (FTBs) transfer cycles. Materials and Methods: The culture of all pronucleate embryos to the blastocyst stage and the se...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2020-02-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/47/1/10.31083/j.ceog.2020.01.5023 |
| _version_ | 1818210746906968064 |
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| author | Y. J. Lee S. C. Kim J. K. Joo H. G. Kim G. R. Ko C. W. Kim K. S. Lee |
| author_facet | Y. J. Lee S. C. Kim J. K. Joo H. G. Kim G. R. Ko C. W. Kim K. S. Lee |
| author_sort | Y. J. Lee |
| collection | DOAJ |
| description | Objective: To investigate the effect of laser-assisted hatching (LAH) compared with mechanical-assisted hatching (MAH) for enhancing clinical outcomes in frozen-thawed blastocysts (FTBs) transfer cycles. Materials and Methods: The culture of all pronucleate embryos to the blastocyst stage and the selection of blastocysts ≥ grade 3BB (Gardner and Schooleraft score), followed by FTBs transfer cycles with LAH (n=105) or with MAH (n=101). Clinical outcomes including clinical and ongoing pregnancy rates were investigated.Results: There were no significant differences in clinical and ongoing pregnancy rates between LAH and MAH groups in FTBs transfer cycles. Conclusion: LAH does not improve pregnancy outcomes significantly compared to MAH in FTBs transfer cycles. |
| first_indexed | 2024-12-12T05:21:31Z |
| format | Article |
| id | doaj.art-5bbc3452d5654bf5bb30744251d84601 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-12-12T05:21:31Z |
| publishDate | 2020-02-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-5bbc3452d5654bf5bb30744251d846012022-12-22T00:36:36ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632020-02-01471656910.31083/j.ceog.2020.01.5023S0390-6663(20)00206-7Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles?Y. J. Lee0S. C. Kim1J. K. Joo2H. G. Kim3G. R. Ko4C. W. Kim5K. S. Lee6Departments of Obstetrics and Gynecology, Medical Research Institute, Pusan National University School of Medicine, Busan, KoreaDepartments of Obstetrics and Gynecology, Medical Research Institute, Pusan National University School of Medicine, Busan, KoreaDepartments of Obstetrics and Gynecology, Medical Research Institute, Pusan National University School of Medicine, Busan, KoreaDepartments of Obstetrics and Gynecology, Medical Research Institute, Pusan National University School of Medicine, Busan, KoreaInfertility Center, Pusan National University Hospital, Busan, KoreaDepartments of Obstetrics and Gynecology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, KoreaDepartments of Obstetrics and Gynecology, Medical Research Institute, Pusan National University School of Medicine, Busan, KoreaObjective: To investigate the effect of laser-assisted hatching (LAH) compared with mechanical-assisted hatching (MAH) for enhancing clinical outcomes in frozen-thawed blastocysts (FTBs) transfer cycles. Materials and Methods: The culture of all pronucleate embryos to the blastocyst stage and the selection of blastocysts ≥ grade 3BB (Gardner and Schooleraft score), followed by FTBs transfer cycles with LAH (n=105) or with MAH (n=101). Clinical outcomes including clinical and ongoing pregnancy rates were investigated.Results: There were no significant differences in clinical and ongoing pregnancy rates between LAH and MAH groups in FTBs transfer cycles. Conclusion: LAH does not improve pregnancy outcomes significantly compared to MAH in FTBs transfer cycles.https://www.imrpress.com/journal/CEOG/47/1/10.31083/j.ceog.2020.01.5023laser-assisted hatchingmechanical-assisted hatchingfrozen-thawed blastocyst |
| spellingShingle | Y. J. Lee S. C. Kim J. K. Joo H. G. Kim G. R. Ko C. W. Kim K. S. Lee Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles? Clinical and Experimental Obstetrics & Gynecology laser-assisted hatching mechanical-assisted hatching frozen-thawed blastocyst |
| title | Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles? |
| title_full | Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles? |
| title_fullStr | Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles? |
| title_full_unstemmed | Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles? |
| title_short | Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles? |
| title_sort | is laser assisted hatching better than mechanical method for enhancing pregnancy rate in frozen thawed blastocyst transfer cycles |
| topic | laser-assisted hatching mechanical-assisted hatching frozen-thawed blastocyst |
| url | https://www.imrpress.com/journal/CEOG/47/1/10.31083/j.ceog.2020.01.5023 |
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