Current Status of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>)
Staphylococcal cassette chromosome <i>mec</i> (SCC<i>mec</i>) typing was established in the 2000s and has been employed as a tool for the molecular epidemiology of methicillin-resistant <i>Staphylococcus aureus</i>, as well as the evolution investigation of <i&...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/11/1/86 |
| _version_ | 1797496298901864448 |
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| author | Yuki Uehara |
| author_facet | Yuki Uehara |
| author_sort | Yuki Uehara |
| collection | DOAJ |
| description | Staphylococcal cassette chromosome <i>mec</i> (SCC<i>mec</i>) typing was established in the 2000s and has been employed as a tool for the molecular epidemiology of methicillin-resistant <i>Staphylococcus aureus</i>, as well as the evolution investigation of <i>Staphylococcus</i> species. Molecular cloning and the conventional sequencing of SCC<i>mec</i> have been adopted to verify the presence and structure of a novel SCC<i>mec</i> type, while convenient PCR-based SCC<i>mec</i> identification methods have been used in practical settings for many years. In addition, whole-genome sequencing has been widely used, and various SCC<i>mec</i> and similar structures have been recently identified in various species. The current status of the SCC<i>mec</i> types, SCC<i>mec</i> subtypes, rules for nomenclature, and multiple methods for identifying SCC<i>mec</i> types and subtypes were summarized in this review, according to the perspective of the International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements. |
| first_indexed | 2024-03-10T03:01:42Z |
| format | Article |
| id | doaj.art-5bc0fe220bd949298e2622e76ab6c56b |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T03:01:42Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-5bc0fe220bd949298e2622e76ab6c56b2023-11-23T12:44:55ZengMDPI AGAntibiotics2079-63822022-01-011118610.3390/antibiotics11010086Current Status of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>)Yuki Uehara0Department of Microbiology, Faculty of Medicine, Juntendo University, Tokyo 113-0033, JapanStaphylococcal cassette chromosome <i>mec</i> (SCC<i>mec</i>) typing was established in the 2000s and has been employed as a tool for the molecular epidemiology of methicillin-resistant <i>Staphylococcus aureus</i>, as well as the evolution investigation of <i>Staphylococcus</i> species. Molecular cloning and the conventional sequencing of SCC<i>mec</i> have been adopted to verify the presence and structure of a novel SCC<i>mec</i> type, while convenient PCR-based SCC<i>mec</i> identification methods have been used in practical settings for many years. In addition, whole-genome sequencing has been widely used, and various SCC<i>mec</i> and similar structures have been recently identified in various species. The current status of the SCC<i>mec</i> types, SCC<i>mec</i> subtypes, rules for nomenclature, and multiple methods for identifying SCC<i>mec</i> types and subtypes were summarized in this review, according to the perspective of the International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements.https://www.mdpi.com/2079-6382/11/1/86methicillin-resistant <i>Staphylococcus aureus</i>staphylococcal cassette chromosome <i>mec</i> (SCC<i>mec</i>)SCC<i>mec</i> typingSCC<i>mec</i> subtypingInternational Working Group on the Classification of Staphylococcal Cassette Chromosome Elements |
| spellingShingle | Yuki Uehara Current Status of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) Antibiotics methicillin-resistant <i>Staphylococcus aureus</i> staphylococcal cassette chromosome <i>mec</i> (SCC<i>mec</i>) SCC<i>mec</i> typing SCC<i>mec</i> subtyping International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements |
| title | Current Status of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) |
| title_full | Current Status of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) |
| title_fullStr | Current Status of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) |
| title_full_unstemmed | Current Status of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) |
| title_short | Current Status of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) |
| title_sort | current status of staphylococcal cassette chromosome i mec i scc i mec i |
| topic | methicillin-resistant <i>Staphylococcus aureus</i> staphylococcal cassette chromosome <i>mec</i> (SCC<i>mec</i>) SCC<i>mec</i> typing SCC<i>mec</i> subtyping International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements |
| url | https://www.mdpi.com/2079-6382/11/1/86 |
| work_keys_str_mv | AT yukiuehara currentstatusofstaphylococcalcassettechromosomeimecisccimeci |