Clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospital
Aim: The aim is to determine the distribution of different classes of lupus nephritis based on renal biopsy and to correlate it with serum creatinine and proteinuria. Objectives: To study the prevalence of different classes of systemic lupus erythematosus (SLE) using the International Society of...
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| Format: | Article |
| Language: | English |
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KIMS Foundation and Research Center
2019-04-01
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| Series: | Journal of Medical and Scientific Research |
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| Online Access: | http://jmsronline.com/article.aspx?ID=Clinicopathological-spectrum-of-patients-with-lupus-nephritis |
| _version_ | 1818525026869051392 |
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| author | Harika Venishetty Sujatha Poduval K Satish Rao I Reddy VS |
| author_facet | Harika Venishetty Sujatha Poduval K Satish Rao I Reddy VS |
| author_sort | Harika Venishetty |
| collection | DOAJ |
| description | Aim: The aim is to determine the distribution of different classes of lupus nephritis based on renal biopsy and to correlate it with serum creatinine and proteinuria.
Objectives: To study the prevalence of different classes of systemic lupus erythematosus (SLE) using the International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2003 classification in our facility, and to determine the correlation between the histopathological features of different classes of lupus nephritis and the clinical and laboratory parameters.
Material and methods: Renal biopsy specimens with a clinical diagnosis of SLE by ARA criteria in a period of 3 years received in the laboratory were included in the study and were classified according ISN/RPS 2003 classification. The clinical and laboratory data were obtained from patient files.
Results: Out of 40 patients, 35 (88%) were females and 5 (12%) were male patients. Mean age was 32.7±10.7 years. Majority of patients belong to class IV (53%) followed by class III (22%).
Conclusion: In this study the commonest class of International Society of Nephrology (ISN)/Renal Pathology Society (RPS) classification is class IV and there is significant correlation between 24 h proteinuria with ISN/RPS classes. |
| first_indexed | 2024-12-11T06:04:21Z |
| format | Article |
| id | doaj.art-5bc200a0f87345c9a9660250f3bbc417 |
| institution | Directory Open Access Journal |
| issn | 2321-1326 2394-112X |
| language | English |
| last_indexed | 2024-12-11T06:04:21Z |
| publishDate | 2019-04-01 |
| publisher | KIMS Foundation and Research Center |
| record_format | Article |
| series | Journal of Medical and Scientific Research |
| spelling | doaj.art-5bc200a0f87345c9a9660250f3bbc4172022-12-22T01:18:22ZengKIMS Foundation and Research CenterJournal of Medical and Scientific Research2321-13262394-112X2019-04-0172364210.17727/JMSR.2019/7-8Clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospitalHarika Venishetty0Sujatha Poduval K1Satish Rao I2Reddy VS3Department of Pathology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaDepartment of Pathology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India Department of Pathology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India Department of Nephrology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaAim: The aim is to determine the distribution of different classes of lupus nephritis based on renal biopsy and to correlate it with serum creatinine and proteinuria. Objectives: To study the prevalence of different classes of systemic lupus erythematosus (SLE) using the International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2003 classification in our facility, and to determine the correlation between the histopathological features of different classes of lupus nephritis and the clinical and laboratory parameters. Material and methods: Renal biopsy specimens with a clinical diagnosis of SLE by ARA criteria in a period of 3 years received in the laboratory were included in the study and were classified according ISN/RPS 2003 classification. The clinical and laboratory data were obtained from patient files. Results: Out of 40 patients, 35 (88%) were females and 5 (12%) were male patients. Mean age was 32.7±10.7 years. Majority of patients belong to class IV (53%) followed by class III (22%). Conclusion: In this study the commonest class of International Society of Nephrology (ISN)/Renal Pathology Society (RPS) classification is class IV and there is significant correlation between 24 h proteinuria with ISN/RPS classes.http://jmsronline.com/article.aspx?ID=Clinicopathological-spectrum-of-patients-with-lupus-nephritissystemic lupus erythematosuslupus nephritisnephritic syndromeautoimmune |
| spellingShingle | Harika Venishetty Sujatha Poduval K Satish Rao I Reddy VS Clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospital Journal of Medical and Scientific Research systemic lupus erythematosus lupus nephritis nephritic syndrome autoimmune |
| title | Clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospital |
| title_full | Clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospital |
| title_fullStr | Clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospital |
| title_full_unstemmed | Clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospital |
| title_short | Clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospital |
| title_sort | clinicopathological spectrum of patients with lupus nephritis in a tertiary care hospital |
| topic | systemic lupus erythematosus lupus nephritis nephritic syndrome autoimmune |
| url | http://jmsronline.com/article.aspx?ID=Clinicopathological-spectrum-of-patients-with-lupus-nephritis |
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