Clinical-pathological features and perioperative outcomes of mediastinoscopy vs. thoracoscopy esophagectomy in esophageal cancer: A meta-analysis
ObjectiveTo compare the clinicopathological features and perioperative outcomes of video-assisted mediastinoscopy esophagectomy (VAME) compared to video-assisted thoracoscopy esophagectomy (VATE) in esophageal cancer.MethodsWe comprehensively searched online databases (PubMed, Embase, Web of Science...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1039615/full |
| _version_ | 1811164297243394048 |
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| author | Sheng Gong Xin Rao Ye Yuan Xiaojun Yao Gang Li Ning Wang Dan Li Liangshuang Jiang |
| author_facet | Sheng Gong Xin Rao Ye Yuan Xiaojun Yao Gang Li Ning Wang Dan Li Liangshuang Jiang |
| author_sort | Sheng Gong |
| collection | DOAJ |
| description | ObjectiveTo compare the clinicopathological features and perioperative outcomes of video-assisted mediastinoscopy esophagectomy (VAME) compared to video-assisted thoracoscopy esophagectomy (VATE) in esophageal cancer.MethodsWe comprehensively searched online databases (PubMed, Embase, Web of Science and Wiley online library) to find available studies exploring the clinicopathological features and perioperative outcomes between VAME and VATE in esophageal cancer. Relative risk (RR) with 95% confidence interval (CI) and standardized mean difference (SMD) with 95% CI were used to evaluate the perioperative outcomes and clinicopathological features.ResultsA total of seven observational studies and one randomized controlled trial involving 733 patients were considered eligible for this meta-analysis, of which 350 patients underwent VAME in contrast to 383 patients underwent VATE. Patients in the VAME group had more pulmonary comorbidities (RR = 2.18, 95% CI 1.37–3.46, P = 0.001). The pooled results showed that VAME shortened the operation time (SMD = −1.53, 95% CI −2.308–−0.76, P = 0.000), and retrieved less total lymph nodes (SMD = −0.70, 95% CI −0.90–−0.50, P = 0.000). No differences were observed in other clinicopathological features, postoperative complications or mortality.ConclusionsThis meta-analysis revealed that patients in the VAME group had more pulmonary disease before surgery. The VAME approach significantly shortened the operation time and retrieved less total lymph nodes and did not increase intra- or postoperative complications. |
| first_indexed | 2024-04-10T15:19:21Z |
| format | Article |
| id | doaj.art-5bc712a77271497d96173cce36426e0c |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-10T15:19:21Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-5bc712a77271497d96173cce36426e0c2023-02-14T16:37:31ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-02-011010.3389/fsurg.2023.10396151039615Clinical-pathological features and perioperative outcomes of mediastinoscopy vs. thoracoscopy esophagectomy in esophageal cancer: A meta-analysisSheng Gong0Xin Rao1Ye Yuan2Xiaojun Yao3Gang Li4Ning Wang5Dan Li6Liangshuang Jiang7Department of Thoracic Surgery, The Public Health Clinical Center of Chengdu, Chengdu, ChinaDepartment of Thoracic Surgery, The Public Health Clinical Center of Chengdu, Chengdu, ChinaDepartment of Thoracic Surgery, The Public Health Clinical Center of Chengdu, Chengdu, ChinaDepartment of Thoracic Surgery, The Public Health Clinical Center of Chengdu, Chengdu, ChinaDepartment of Thoracic Surgery, The Public Health Clinical Center of Chengdu, Chengdu, ChinaDepartment of Public Health, Chengdu Medicine College, Chengdu, ChinaDepartment of Thoracic Surgery, The Public Health Clinical Center of Chengdu, Chengdu, ChinaDepartment of Thoracic Surgery, The Public Health Clinical Center of Chengdu, Chengdu, ChinaObjectiveTo compare the clinicopathological features and perioperative outcomes of video-assisted mediastinoscopy esophagectomy (VAME) compared to video-assisted thoracoscopy esophagectomy (VATE) in esophageal cancer.MethodsWe comprehensively searched online databases (PubMed, Embase, Web of Science and Wiley online library) to find available studies exploring the clinicopathological features and perioperative outcomes between VAME and VATE in esophageal cancer. Relative risk (RR) with 95% confidence interval (CI) and standardized mean difference (SMD) with 95% CI were used to evaluate the perioperative outcomes and clinicopathological features.ResultsA total of seven observational studies and one randomized controlled trial involving 733 patients were considered eligible for this meta-analysis, of which 350 patients underwent VAME in contrast to 383 patients underwent VATE. Patients in the VAME group had more pulmonary comorbidities (RR = 2.18, 95% CI 1.37–3.46, P = 0.001). The pooled results showed that VAME shortened the operation time (SMD = −1.53, 95% CI −2.308–−0.76, P = 0.000), and retrieved less total lymph nodes (SMD = −0.70, 95% CI −0.90–−0.50, P = 0.000). No differences were observed in other clinicopathological features, postoperative complications or mortality.ConclusionsThis meta-analysis revealed that patients in the VAME group had more pulmonary disease before surgery. The VAME approach significantly shortened the operation time and retrieved less total lymph nodes and did not increase intra- or postoperative complications.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1039615/fullesophageal cancermediastinoscopythoracoscopyesophagectomyperioperative outcomes |
| spellingShingle | Sheng Gong Xin Rao Ye Yuan Xiaojun Yao Gang Li Ning Wang Dan Li Liangshuang Jiang Clinical-pathological features and perioperative outcomes of mediastinoscopy vs. thoracoscopy esophagectomy in esophageal cancer: A meta-analysis Frontiers in Surgery esophageal cancer mediastinoscopy thoracoscopy esophagectomy perioperative outcomes |
| title | Clinical-pathological features and perioperative outcomes of mediastinoscopy vs. thoracoscopy esophagectomy in esophageal cancer: A meta-analysis |
| title_full | Clinical-pathological features and perioperative outcomes of mediastinoscopy vs. thoracoscopy esophagectomy in esophageal cancer: A meta-analysis |
| title_fullStr | Clinical-pathological features and perioperative outcomes of mediastinoscopy vs. thoracoscopy esophagectomy in esophageal cancer: A meta-analysis |
| title_full_unstemmed | Clinical-pathological features and perioperative outcomes of mediastinoscopy vs. thoracoscopy esophagectomy in esophageal cancer: A meta-analysis |
| title_short | Clinical-pathological features and perioperative outcomes of mediastinoscopy vs. thoracoscopy esophagectomy in esophageal cancer: A meta-analysis |
| title_sort | clinical pathological features and perioperative outcomes of mediastinoscopy vs thoracoscopy esophagectomy in esophageal cancer a meta analysis |
| topic | esophageal cancer mediastinoscopy thoracoscopy esophagectomy perioperative outcomes |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1039615/full |
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