Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System
New streamlined models for genetic counseling and genetic testing have recently been developed in response to increasing demand for cancer genetic services. To improve access and decrease wait times, we implemented an oncology clinic-based genetic testing model for breast and ovarian cancer patients...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-02-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/12/2/338 |
| _version_ | 1797757598900944896 |
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| author | Matthew Richardson Hae Jung Min Quan Hong Katie Compton Sze Wing Mung Zoe Lohn Jennifer Nuk Mary McCullum Cheryl Portigal-Todd Aly Karsan Dean Regier Lori A. Brotto Sophie Sun Kasmintan A. Schrader |
| author_facet | Matthew Richardson Hae Jung Min Quan Hong Katie Compton Sze Wing Mung Zoe Lohn Jennifer Nuk Mary McCullum Cheryl Portigal-Todd Aly Karsan Dean Regier Lori A. Brotto Sophie Sun Kasmintan A. Schrader |
| author_sort | Matthew Richardson |
| collection | DOAJ |
| description | New streamlined models for genetic counseling and genetic testing have recently been developed in response to increasing demand for cancer genetic services. To improve access and decrease wait times, we implemented an oncology clinic-based genetic testing model for breast and ovarian cancer patients in a publicly funded population-based health care setting in British Columbia, Canada. This observational study evaluated the oncology clinic-based model as compared to a traditional one-on-one approach with a genetic counsellor using a multi-gene panel testing approach. The primary objectives were to evaluate wait times and patient reported outcome measures between the oncology clinic-based and traditional genetic counselling models. Secondary objectives were to describe oncologist and genetic counsellor acceptability and experience. Wait times from referral to return of genetic testing results were assessed for 400 patients with breast and/or ovarian cancer undergoing genetic testing for hereditary breast and ovarian cancer from June 2015 to August 2017. Patient wait times from referral to return of results were significantly shorter with the oncology clinic-based model as compared to the traditional model (403 vs. 191 days; <i>p</i> < 0.001). A subset of 148 patients (traditional <i>n</i> = 99; oncology clinic-based <i>n</i> = 49) completed study surveys to assess uncertainty, distress, and patient experience. Responses were similar between both models. Healthcare providers survey responses indicated they believed the oncology clinic-based model was acceptable and a positive experience. Oncology clinic-based genetic testing using a multi-gene panel approach and post-test counselling with a genetic counsellor significantly reduced wait times and is acceptable for patients and health care providers. |
| first_indexed | 2024-03-12T18:18:08Z |
| format | Article |
| id | doaj.art-5bc71544b42b42e0afea17329ee3ae22 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T18:18:08Z |
| publishDate | 2020-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-5bc71544b42b42e0afea17329ee3ae222023-08-02T09:01:16ZengMDPI AGCancers2072-66942020-02-0112233810.3390/cancers12020338cancers12020338Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care SystemMatthew Richardson0Hae Jung Min1Quan Hong2Katie Compton3Sze Wing Mung4Zoe Lohn5Jennifer Nuk6Mary McCullum7Cheryl Portigal-Todd8Aly Karsan9Dean Regier10Lori A. Brotto11Sophie Sun12Kasmintan A. Schrader13Interdisciplinary Oncology Program, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 2B5, CanadaDepartment of School of Population and Public Health, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, CanadaDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of British Columbia, Vancouver, BC V6Z 2K8, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaHereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, CanadaNew streamlined models for genetic counseling and genetic testing have recently been developed in response to increasing demand for cancer genetic services. To improve access and decrease wait times, we implemented an oncology clinic-based genetic testing model for breast and ovarian cancer patients in a publicly funded population-based health care setting in British Columbia, Canada. This observational study evaluated the oncology clinic-based model as compared to a traditional one-on-one approach with a genetic counsellor using a multi-gene panel testing approach. The primary objectives were to evaluate wait times and patient reported outcome measures between the oncology clinic-based and traditional genetic counselling models. Secondary objectives were to describe oncologist and genetic counsellor acceptability and experience. Wait times from referral to return of genetic testing results were assessed for 400 patients with breast and/or ovarian cancer undergoing genetic testing for hereditary breast and ovarian cancer from June 2015 to August 2017. Patient wait times from referral to return of results were significantly shorter with the oncology clinic-based model as compared to the traditional model (403 vs. 191 days; <i>p</i> < 0.001). A subset of 148 patients (traditional <i>n</i> = 99; oncology clinic-based <i>n</i> = 49) completed study surveys to assess uncertainty, distress, and patient experience. Responses were similar between both models. Healthcare providers survey responses indicated they believed the oncology clinic-based model was acceptable and a positive experience. Oncology clinic-based genetic testing using a multi-gene panel approach and post-test counselling with a genetic counsellor significantly reduced wait times and is acceptable for patients and health care providers.https://www.mdpi.com/2072-6694/12/2/338hereditary cancergenetic counsellinggenetic testingpatient reported outcome measures |
| spellingShingle | Matthew Richardson Hae Jung Min Quan Hong Katie Compton Sze Wing Mung Zoe Lohn Jennifer Nuk Mary McCullum Cheryl Portigal-Todd Aly Karsan Dean Regier Lori A. Brotto Sophie Sun Kasmintan A. Schrader Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System Cancers hereditary cancer genetic counselling genetic testing patient reported outcome measures |
| title | Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System |
| title_full | Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System |
| title_fullStr | Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System |
| title_full_unstemmed | Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System |
| title_short | Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System |
| title_sort | oncology clinic based hereditary cancer genetic testing in a population based health care system |
| topic | hereditary cancer genetic counselling genetic testing patient reported outcome measures |
| url | https://www.mdpi.com/2072-6694/12/2/338 |
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