Serum cortisol is negatively related to hippocampal volume, brain structure, and memory performance in healthy aging and Alzheimer’s disease

Serum cortisol is negatively related to hippocampal volume, brain structure, and memory performance in healthy aging and Alzheimer’s disease

ObjectiveElevated cortisol levels have been frequently reported in Alzheimer’s disease (AD) and linked to brain atrophy, especially of the hippocampus. Besides, high cortisol levels have been shown to impair memory performance and increase the risk of developing AD in healthy individuals. We investi...

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Bibliographic Details
Main Authors: Julian Dronse, Anna Ohndorf, Nils Richter, Gérard N. Bischof, Ronja Fassbender, Qumars Behfar, Hannes Gramespacher, Kim Dillen, Heidi I. L. Jacobs, Juraj Kukolja, Gereon R. Fink, Oezguer A. Onur
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
dementia
glucocorticoids
mild cognitive impairment (MCI)
atrophy
voxel-based morphometry (VBM)
Hippocampus
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1154112/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1154112/full

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