Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applications
The development of nanotechnology has a major impact on pharmaceutical sciences, dramatically improving diagnosis and treatment of many diseases that are life-threatening. A number of metallic nanoparticles are widely employed as nanomedicines because they may have medicinal applications. The enviro...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715624000870 |
| _version_ | 1797279254561423360 |
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| author | M.A. Pavan Kumar D. Suresh A.H. Sneharani |
| author_facet | M.A. Pavan Kumar D. Suresh A.H. Sneharani |
| author_sort | M.A. Pavan Kumar |
| collection | DOAJ |
| description | The development of nanotechnology has a major impact on pharmaceutical sciences, dramatically improving diagnosis and treatment of many diseases that are life-threatening. A number of metallic nanoparticles are widely employed as nanomedicines because they may have medicinal applications. The environmental pollution from textile industry is one the big global problems that pose substantial risks to the environment and public health. Finding affordable, efficient, and sustainable technology to solve the challenges with pollution is crucial. In the present study we developed multi-functional Ag-doped CuO nanoparticles by utilizing Actinidia delicia extract by employing solution combustion method. The synthesized nanoparticles were examined by Transmission electron microscopy, scanning electron microscopy including energy dispersion X-ray analysis (EDX), X-ray diffraction (XRD), Fourier transform infrared spectroscopy, and UV–visible spectroscopy. The synthesized nanoparticles have a variety of applications including anticancer, antibacterial, and antidiabetic agents via modulating the activities of carbohydrate digesting enzymes, and they also exhibit effective photocatalytic activity by degrading the methylene blue dye. Platelet aggregation and plasma coagulation were both enhanced by Ag-doped copper oxide nanoparticles, and this was achieved without any noticeable haemolytic activity. This study presents an eco-friendly method for producing multifunctional Ag-CuO nanoparticles. |
| first_indexed | 2024-03-07T16:22:36Z |
| format | Article |
| id | doaj.art-5bc7ac174d554321913d670e24849c56 |
| institution | Directory Open Access Journal |
| issn | 2211-7156 |
| language | English |
| last_indexed | 2024-03-07T16:22:36Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj.art-5bc7ac174d554321913d670e24849c562024-03-04T04:12:05ZengElsevierResults in Chemistry2211-71562024-01-017101391Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applicationsM.A. Pavan Kumar0D. Suresh1A.H. Sneharani2Department of Studies and Research in Biochemistry, Jnana Kaveri PG Centre, Mangalore University, Chikka Aluvara, Kodagu 571232, Karnataka, IndiaDepartment of Chemistry, UCS, Tumkur University, Tumakuru 572103, Karnataka, India; Department of Studies and research in Organic Chemistry, Tumkur University, Tumakuru 572103, Karnataka, India; Corresponding authors at: Department of Chemistry, UCS, Tumkur University, Tumakuru 572103, Karnataka, India.Department of Studies and Research in Biochemistry, Jnana Kaveri PG Centre, Mangalore University, Chikka Aluvara, Kodagu 571232, Karnataka, India; Corresponding authors at: Department of Chemistry, UCS, Tumkur University, Tumakuru 572103, Karnataka, India.The development of nanotechnology has a major impact on pharmaceutical sciences, dramatically improving diagnosis and treatment of many diseases that are life-threatening. A number of metallic nanoparticles are widely employed as nanomedicines because they may have medicinal applications. The environmental pollution from textile industry is one the big global problems that pose substantial risks to the environment and public health. Finding affordable, efficient, and sustainable technology to solve the challenges with pollution is crucial. In the present study we developed multi-functional Ag-doped CuO nanoparticles by utilizing Actinidia delicia extract by employing solution combustion method. The synthesized nanoparticles were examined by Transmission electron microscopy, scanning electron microscopy including energy dispersion X-ray analysis (EDX), X-ray diffraction (XRD), Fourier transform infrared spectroscopy, and UV–visible spectroscopy. The synthesized nanoparticles have a variety of applications including anticancer, antibacterial, and antidiabetic agents via modulating the activities of carbohydrate digesting enzymes, and they also exhibit effective photocatalytic activity by degrading the methylene blue dye. Platelet aggregation and plasma coagulation were both enhanced by Ag-doped copper oxide nanoparticles, and this was achieved without any noticeable haemolytic activity. This study presents an eco-friendly method for producing multifunctional Ag-CuO nanoparticles.http://www.sciencedirect.com/science/article/pii/S2211715624000870CuO nanoparticlesActinidia deliciosaPhotocatalytic activityAnticancerAntidiabeticAntioxidant and antibacterial agent |
| spellingShingle | M.A. Pavan Kumar D. Suresh A.H. Sneharani Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applications Results in Chemistry CuO nanoparticles Actinidia deliciosa Photocatalytic activity Anticancer Antidiabetic Antioxidant and antibacterial agent |
| title | Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applications |
| title_full | Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applications |
| title_fullStr | Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applications |
| title_full_unstemmed | Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applications |
| title_short | Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applications |
| title_sort | eco friendly ag cuo nanoparticles for antidiabetic antimicrobial anti cancer platelet aggregation inducing antioxidant and photocatalytic applications |
| topic | CuO nanoparticles Actinidia deliciosa Photocatalytic activity Anticancer Antidiabetic Antioxidant and antibacterial agent |
| url | http://www.sciencedirect.com/science/article/pii/S2211715624000870 |
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