Eucommia ulmoides Oliver repairs the disorder of intestinal microflora caused by high starch in Micropterus salmoides and improves resistance to pathogens
Eucommia ulmoides Oliver (EuO) is a natural medicine that can improve the composition of intestinal flora in fish, but more experiments and data are needed to support whether it can effectively improve the changes of intestinal flora and intestinal damage caused by high starch. This study examined t...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1223723/full |
| _version_ | 1827810648803770368 |
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| author | Hongli Liu Fulong Li Hong Tang Baipeng Chen Yi Geng Defang Chen Ping Ouyang Liangyu Li Xiaoli Huang |
| author_facet | Hongli Liu Fulong Li Hong Tang Baipeng Chen Yi Geng Defang Chen Ping Ouyang Liangyu Li Xiaoli Huang |
| author_sort | Hongli Liu |
| collection | DOAJ |
| description | Eucommia ulmoides Oliver (EuO) is a natural medicine that can improve the composition of intestinal flora in fish, but more experiments and data are needed to support whether it can effectively improve the changes of intestinal flora and intestinal damage caused by high starch. This study examined the changes in intestinal structure as well as intestinal flora before and after the addition of EuO to high-starch diets and analyzed the effects of such changes on immune and digestive functions. The results showed that EuO reduces mortality during Nocardia seriolae attack and can reduce starch-induced intestinal inflammation. Eucommia ulmoides Oliver supplementation was able to alter the changes of intestinal flora in fatty acid degradation, bacterial chemotaxis, porphyrin metabolism and flagella assembly caused by high starch. By analyzing the abundance and correlation of bacterial communities, three bacterial communities that were significantly related to the intervention effect of EuO were screened. Further analysis revealed that EuO supplementation reduced the increase in abundance of Limnochordaceae, Nitrolancea, Lysinibacillus, and Hydrogenispora induced by high starch, which were negatively correlated with levels of the immunoreactive substance LZM in fish. This study reveals the regulatory effects of EuO on the intestinal flora of Micropterus salmoides fed on high starch diets, and provides a theoretical basis for reducing starch damage to fish in production. |
| first_indexed | 2024-03-11T22:54:37Z |
| format | Article |
| id | doaj.art-5bc8037c66eb4460ba3c13908a0cd436 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-03-11T22:54:37Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-5bc8037c66eb4460ba3c13908a0cd4362023-09-21T18:53:59ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2023-09-011410.3389/fmicb.2023.12237231223723Eucommia ulmoides Oliver repairs the disorder of intestinal microflora caused by high starch in Micropterus salmoides and improves resistance to pathogensHongli Liu0Fulong Li1Hong Tang2Baipeng Chen3Yi Geng4Defang Chen5Ping Ouyang6Liangyu Li7Xiaoli Huang8Department of Aquaculture, College of Animal Science & Technology, Sichuan Agricultural University, Chengdu, Sichuan, ChinaDepartment of Aquaculture, College of Animal Science & Technology, Sichuan Agricultural University, Chengdu, Sichuan, ChinaFisheries Research Institute, Chengdu Academy of Agriculture and Forestry Sciences, Chengdu, Sichuan, ChinaDepartment of Aquaculture, College of Animal Science & Technology, Sichuan Agricultural University, Chengdu, Sichuan, ChinaDepartment of Basic Veterinary, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, ChinaDepartment of Aquaculture, College of Animal Science & Technology, Sichuan Agricultural University, Chengdu, Sichuan, ChinaDepartment of Basic Veterinary, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, ChinaFisheries Research Institute, Chengdu Academy of Agriculture and Forestry Sciences, Chengdu, Sichuan, ChinaDepartment of Aquaculture, College of Animal Science & Technology, Sichuan Agricultural University, Chengdu, Sichuan, ChinaEucommia ulmoides Oliver (EuO) is a natural medicine that can improve the composition of intestinal flora in fish, but more experiments and data are needed to support whether it can effectively improve the changes of intestinal flora and intestinal damage caused by high starch. This study examined the changes in intestinal structure as well as intestinal flora before and after the addition of EuO to high-starch diets and analyzed the effects of such changes on immune and digestive functions. The results showed that EuO reduces mortality during Nocardia seriolae attack and can reduce starch-induced intestinal inflammation. Eucommia ulmoides Oliver supplementation was able to alter the changes of intestinal flora in fatty acid degradation, bacterial chemotaxis, porphyrin metabolism and flagella assembly caused by high starch. By analyzing the abundance and correlation of bacterial communities, three bacterial communities that were significantly related to the intervention effect of EuO were screened. Further analysis revealed that EuO supplementation reduced the increase in abundance of Limnochordaceae, Nitrolancea, Lysinibacillus, and Hydrogenispora induced by high starch, which were negatively correlated with levels of the immunoreactive substance LZM in fish. This study reveals the regulatory effects of EuO on the intestinal flora of Micropterus salmoides fed on high starch diets, and provides a theoretical basis for reducing starch damage to fish in production.https://www.frontiersin.org/articles/10.3389/fmicb.2023.1223723/fullEucommia ulmoides OliverMicropterus salmoidesintestinal microflorastarchimmune |
| spellingShingle | Hongli Liu Fulong Li Hong Tang Baipeng Chen Yi Geng Defang Chen Ping Ouyang Liangyu Li Xiaoli Huang Eucommia ulmoides Oliver repairs the disorder of intestinal microflora caused by high starch in Micropterus salmoides and improves resistance to pathogens Frontiers in Microbiology Eucommia ulmoides Oliver Micropterus salmoides intestinal microflora starch immune |
| title | Eucommia ulmoides Oliver repairs the disorder of intestinal microflora caused by high starch in Micropterus salmoides and improves resistance to pathogens |
| title_full | Eucommia ulmoides Oliver repairs the disorder of intestinal microflora caused by high starch in Micropterus salmoides and improves resistance to pathogens |
| title_fullStr | Eucommia ulmoides Oliver repairs the disorder of intestinal microflora caused by high starch in Micropterus salmoides and improves resistance to pathogens |
| title_full_unstemmed | Eucommia ulmoides Oliver repairs the disorder of intestinal microflora caused by high starch in Micropterus salmoides and improves resistance to pathogens |
| title_short | Eucommia ulmoides Oliver repairs the disorder of intestinal microflora caused by high starch in Micropterus salmoides and improves resistance to pathogens |
| title_sort | eucommia ulmoides oliver repairs the disorder of intestinal microflora caused by high starch in micropterus salmoides and improves resistance to pathogens |
| topic | Eucommia ulmoides Oliver Micropterus salmoides intestinal microflora starch immune |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1223723/full |
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