Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory study

Background: Undenatured type-II collagen (UC-II®) has demonstrated its benefits in degenerative joint disease (DJD) management. Aim: Exploratory clinical study to investigate the beneficial effects of, FLEXADIN® Advanced in dogs. Methods: Multicentre clinical prospective study, 110 client-owned...

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Bibliographic Details
Main Authors: Miguel Ángel Cabezas, Javier Benito, Álvaro Ortega, Elena Garcia-Pedraza
Format: Article
Language:English
Published: Tripoli University 2022-02-01
Series:Open Veterinary Journal
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Online Access:https://www.openveterinaryjournal.com/OVJ-2021-05-096%20M.A.%20Cabezas%20et%20al.pdf
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Summary:Background: Undenatured type-II collagen (UC-II®) has demonstrated its benefits in degenerative joint disease (DJD) management. Aim: Exploratory clinical study to investigate the beneficial effects of, FLEXADIN® Advanced in dogs. Methods: Multicentre clinical prospective study, 110 client-owned dogs with a clinical diagnosis of DJD. Dogs received FLEXADIN® Advanced during 6 months. Pain, general condition, appetite, mobility and lameness was assessed monthly by veterinarians and owners for 6 months. Compliance was assessed at 3 and 6 months. Statistical analysis was performed with non-parametric tests (significance, P< 0.05). Results: Parameters assessed were significantly lower comparing inclusion with all subsequent months (p < 0.0001). Compliance at 3 months showed a good score but was significantly lower (p < 0.0001) at six months. Conclusion: FLEXADIN® Advanced, containing UC-II®, can be considered a good complementary feed to provide joint support in dogs with mild to moderate DJD.
ISSN:2226-4485
2218-6050