Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory study
Background: Undenatured type-II collagen (UC-II®) has demonstrated its benefits in degenerative joint disease (DJD) management. Aim: Exploratory clinical study to investigate the beneficial effects of, FLEXADIN® Advanced in dogs. Methods: Multicentre clinical prospective study, 110 client-owned...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Tripoli University
2022-02-01
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| Series: | Open Veterinary Journal |
| Subjects: | |
| Online Access: | https://www.openveterinaryjournal.com/OVJ-2021-05-096%20M.A.%20Cabezas%20et%20al.pdf |
| _version_ | 1819279322287964160 |
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| author | Miguel Ángel Cabezas Javier Benito Álvaro Ortega Elena Garcia-Pedraza |
| author_facet | Miguel Ángel Cabezas Javier Benito Álvaro Ortega Elena Garcia-Pedraza |
| author_sort | Miguel Ángel Cabezas |
| collection | DOAJ |
| description | Background: Undenatured type-II collagen (UC-II®) has demonstrated its benefits in degenerative joint disease (DJD) management.
Aim: Exploratory clinical study to investigate the beneficial effects of, FLEXADIN® Advanced in dogs.
Methods: Multicentre clinical prospective study, 110 client-owned dogs with a clinical diagnosis of DJD. Dogs received FLEXADIN® Advanced during 6 months. Pain, general condition, appetite, mobility and lameness was assessed monthly by veterinarians and owners for 6 months. Compliance was assessed at 3 and 6 months. Statistical analysis was performed with non-parametric tests (significance, P< 0.05).
Results: Parameters assessed were significantly lower comparing inclusion with all subsequent months (p < 0.0001). Compliance at 3 months showed a good score but was significantly lower (p < 0.0001) at six months.
Conclusion: FLEXADIN® Advanced, containing UC-II®, can be considered a good complementary feed to provide joint support in dogs with mild to moderate DJD. |
| first_indexed | 2024-12-24T00:26:04Z |
| format | Article |
| id | doaj.art-5bc84853b7634821bd4af276cf2b31ee |
| institution | Directory Open Access Journal |
| issn | 2226-4485 2218-6050 |
| language | English |
| last_indexed | 2024-12-24T00:26:04Z |
| publishDate | 2022-02-01 |
| publisher | Tripoli University |
| record_format | Article |
| series | Open Veterinary Journal |
| spelling | doaj.art-5bc84853b7634821bd4af276cf2b31ee2022-12-21T17:24:26ZengTripoli UniversityOpen Veterinary Journal2226-44852218-60502022-02-01121919810.5455/OVJ.2022.v12.i1.11Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory studyMiguel Ángel Cabezas0Javier Benito1Álvaro Ortega2Elena Garcia-Pedraza3Avda. Puerta de Hierro s/n. 28040, Madrid, SpainDepartment of Clinical Sciences, Faculty of Veterinary Medicine, University of Montreal UdeM, St-Hyacinthe, Quebec, J2S 2M2, CanadaRoad Fuencarral 24, Edificio Europa I portal 3, 25. 28108, Alcobendas, Madrid, Spain37 Rue de la Victoire 2 floor, 75009, Paris, FranceBackground: Undenatured type-II collagen (UC-II®) has demonstrated its benefits in degenerative joint disease (DJD) management. Aim: Exploratory clinical study to investigate the beneficial effects of, FLEXADIN® Advanced in dogs. Methods: Multicentre clinical prospective study, 110 client-owned dogs with a clinical diagnosis of DJD. Dogs received FLEXADIN® Advanced during 6 months. Pain, general condition, appetite, mobility and lameness was assessed monthly by veterinarians and owners for 6 months. Compliance was assessed at 3 and 6 months. Statistical analysis was performed with non-parametric tests (significance, P< 0.05). Results: Parameters assessed were significantly lower comparing inclusion with all subsequent months (p < 0.0001). Compliance at 3 months showed a good score but was significantly lower (p < 0.0001) at six months. Conclusion: FLEXADIN® Advanced, containing UC-II®, can be considered a good complementary feed to provide joint support in dogs with mild to moderate DJD.https://www.openveterinaryjournal.com/OVJ-2021-05-096%20M.A.%20Cabezas%20et%20al.pdfuc-iidogdegenerative joint diseasesupplementcompliance |
| spellingShingle | Miguel Ángel Cabezas Javier Benito Álvaro Ortega Elena Garcia-Pedraza Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory study Open Veterinary Journal uc-ii dog degenerative joint disease supplement compliance |
| title | Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory study |
| title_full | Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory study |
| title_fullStr | Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory study |
| title_full_unstemmed | Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory study |
| title_short | Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: Exploratory study |
| title_sort | long term supplementation with an undenatured type ii collagen uc ii r formulation in dogs with degenerative joint disease exploratory study |
| topic | uc-ii dog degenerative joint disease supplement compliance |
| url | https://www.openveterinaryjournal.com/OVJ-2021-05-096%20M.A.%20Cabezas%20et%20al.pdf |
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