Novel Cysteine Protease Inhibitor Derived from the <i>Haementeria vizottoi</i> Leech: Recombinant Expression, Purification, and Characterization

Novel Cysteine Protease Inhibitor Derived from the <i>Haementeria vizottoi</i> Leech: Recombinant Expression, Purification, and Characterization

Cathepsin L (CatL) is a lysosomal cysteine protease primarily involved in the terminal degradation of intracellular and endocytosed proteins. More specifically, in humans, CatL has been implicated in cancer progression and metastasis, as well as coronary artery diseases and others. Given this, the s...

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Bibliographic Details
Main Authors: Débora do Carmo Linhares, Fernanda Faria, Roberto Tadashi Kodama, Adriane Michele Xavier Prado Amorim, Fernanda Calheta Vieira Portaro, Dilza Trevisan-Silva, Karla Fernanda Ferraz, Ana Marisa Chudzinski-Tavassi
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Toxins
Subjects:
leech
<i>Haementeria vizottoi</i>
cysteine proteases inhibitor
recombinant cystatin
cathepsin L
Online Access:https://www.mdpi.com/2072-6651/13/12/857

Internet

https://www.mdpi.com/2072-6651/13/12/857

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