Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq

Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq

The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaricidal drug. Flubendazole (FLBZ), a benzimidazole an...

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Bibliographic Details
Main Authors: Maeghan O'Neill, Cristina Ballesteros, Lucienne Tritten, Erica Burkman, Weam I. Zaky, Jianguo Xia, Andrew Moorhead, Steven A. Williams, Timothy G. Geary
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Filariasis
Macrofilaricide
Benzimidazole
RNAseq
Reproduction
Cuticle
Flubendazole
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320716300562

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