N-carboxymethyl chitosan/sodium alginate composite hydrogel loading plasmid DNA as a promising gene activated matrix for in-situ burn wound treatment

N-carboxymethyl chitosan/sodium alginate composite hydrogel loading plasmid DNA as a promising gene activated matrix for in-situ burn wound treatment

Improving the degree of vascularization through the regulation of wound microenvironment is crucial for wound repair. Gene activated matrix (GAM) technology provides a new approach for skin regeneration. It is a local gene delivery system that can not only maintain a moist environment, but also incr...

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Bibliographic Details
Main Authors: Litong Wang, Le Sun, Zhiyang Gu, Wenya Li, Lili Guo, Saibo Ma, Lan Guo, Wangwang Zhang, Baoqin Han, Jing Chang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-09-01
Series:Bioactive Materials
Subjects:
Gene activated matrix
Hydrogel
Wounds healing
N-carboxymethyl chitosan
Sodium alginate
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21005843

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