GATA1 mutation negative acute megakaryoblastic leukemia with acquired trisomy 21 presenting with extensive bone marrow necrosis in an adult: A case report and review of the literature
Context: Acute megakaryoblastic leukemia (AMKL) is a rare myeloid leukemia, occurring in 1%–5% of all adult acute myeloid leukemia (AML) cases. AMKL is characterized by a leukemic blast population positive for factor VIII, CD41a, CD42b, and/or CD61 with extensive myelofibrosis. Although various cyto...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-03-01
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| Series: | Human Pathology: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214330015300341 |