Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology
Oxidative stress represents one of the main factors driving the pathophysiology of multiple ophthalmic conditions including presbyopia, cataracts, dry eye disease (DED), glaucoma, age-related macular degeneration (AMD) and diabetic retinopathy (DR). Currently, different studies have demonstrated the...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/14/23/5014 |
| _version_ | 1797462513140367360 |
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| author | Carlos Rodrigo Castro-Castaneda Francisco Altamirano-Lamarque Alan Gabriel Ortega-Macías Francisco J. Santa Cruz-Pavlovich Alejandro Gonzalez-De la Rosa Juan Armendariz-Borunda Arturo Santos Jose Navarro-Partida |
| author_facet | Carlos Rodrigo Castro-Castaneda Francisco Altamirano-Lamarque Alan Gabriel Ortega-Macías Francisco J. Santa Cruz-Pavlovich Alejandro Gonzalez-De la Rosa Juan Armendariz-Borunda Arturo Santos Jose Navarro-Partida |
| author_sort | Carlos Rodrigo Castro-Castaneda |
| collection | DOAJ |
| description | Oxidative stress represents one of the main factors driving the pathophysiology of multiple ophthalmic conditions including presbyopia, cataracts, dry eye disease (DED), glaucoma, age-related macular degeneration (AMD) and diabetic retinopathy (DR). Currently, different studies have demonstrated the role of orally administered nutraceuticals in these diseases. For instance, they have demonstrated to improve lens accommodation in presbyopia, reduce protein aggregation in cataracts, ameliorate tear film stability, break up time, and tear production in dry eye, and participate in the avoidance of retinal neuronal damage and a decrease in intraocular pressure in glaucoma, contribute to the delayed progression of AMD, or in the prevention or treatment of neuronal death in diabetic retinopathy. In this review, we summarized the nutraceuticals which have presented a positive impact in ocular disorders, emphasizing the clinical assays. The characteristics of the different types of nutraceuticals are specified along with the nutraceutical concentration used to achieve a therapeutic outcome in ocular diseases. |
| first_indexed | 2024-03-09T17:37:38Z |
| format | Article |
| id | doaj.art-5bdb635242804f00a326e3ef87484684 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T17:37:38Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-5bdb635242804f00a326e3ef874846842023-11-24T11:50:41ZengMDPI AGNutrients2072-66432022-11-011423501410.3390/nu14235014Nutraceuticals: A Promising Therapeutic Approach in OphthalmologyCarlos Rodrigo Castro-Castaneda0Francisco Altamirano-Lamarque1Alan Gabriel Ortega-Macías2Francisco J. Santa Cruz-Pavlovich3Alejandro Gonzalez-De la Rosa4Juan Armendariz-Borunda5Arturo Santos6Jose Navarro-Partida7Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Zapopan 45138, MexicoTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Zapopan 45138, MexicoTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Zapopan 45138, MexicoTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Zapopan 45138, MexicoTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Zapopan 45138, MexicoTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Zapopan 45138, MexicoTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Zapopan 45138, MexicoTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Zapopan 45138, MexicoOxidative stress represents one of the main factors driving the pathophysiology of multiple ophthalmic conditions including presbyopia, cataracts, dry eye disease (DED), glaucoma, age-related macular degeneration (AMD) and diabetic retinopathy (DR). Currently, different studies have demonstrated the role of orally administered nutraceuticals in these diseases. For instance, they have demonstrated to improve lens accommodation in presbyopia, reduce protein aggregation in cataracts, ameliorate tear film stability, break up time, and tear production in dry eye, and participate in the avoidance of retinal neuronal damage and a decrease in intraocular pressure in glaucoma, contribute to the delayed progression of AMD, or in the prevention or treatment of neuronal death in diabetic retinopathy. In this review, we summarized the nutraceuticals which have presented a positive impact in ocular disorders, emphasizing the clinical assays. The characteristics of the different types of nutraceuticals are specified along with the nutraceutical concentration used to achieve a therapeutic outcome in ocular diseases.https://www.mdpi.com/2072-6643/14/23/5014nutraceuticaloxidative stressantioxidantophthalmic diseases |
| spellingShingle | Carlos Rodrigo Castro-Castaneda Francisco Altamirano-Lamarque Alan Gabriel Ortega-Macías Francisco J. Santa Cruz-Pavlovich Alejandro Gonzalez-De la Rosa Juan Armendariz-Borunda Arturo Santos Jose Navarro-Partida Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology Nutrients nutraceutical oxidative stress antioxidant ophthalmic diseases |
| title | Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology |
| title_full | Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology |
| title_fullStr | Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology |
| title_full_unstemmed | Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology |
| title_short | Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology |
| title_sort | nutraceuticals a promising therapeutic approach in ophthalmology |
| topic | nutraceutical oxidative stress antioxidant ophthalmic diseases |
| url | https://www.mdpi.com/2072-6643/14/23/5014 |
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