Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient
As a result of the COVID-19 pandemic, mRNA vaccination has become widespread. Recently, it has been suggested that instances of herpes zoster increase following mRNA COVID-19 vaccination. Herein, we describe the first case of zoster sine herpete (ZSH) after mRNA vaccination for COVID-19. A 60-year-o...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250922001913 |
| _version_ | 1817995035507949568 |
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| author | Ryutaro Tanizaki Yayoi Miyamatsu |
| author_facet | Ryutaro Tanizaki Yayoi Miyamatsu |
| author_sort | Ryutaro Tanizaki |
| collection | DOAJ |
| description | As a result of the COVID-19 pandemic, mRNA vaccination has become widespread. Recently, it has been suggested that instances of herpes zoster increase following mRNA COVID-19 vaccination. Herein, we describe the first case of zoster sine herpete (ZSH) after mRNA vaccination for COVID-19. A 60-year-old Japanese immunocompetent man presented with fever, fatigue, headache, cervical pain, and lumbar pain, which developed after receiving a second dose of BNT162b2 mRNA COVID-19 vaccination. Whereas most symptoms improved with symptomatic treatment, headache and numbness of the right forehead persisted in areas innervated by the trigeminal and second and third cervical nerves. Based on positive results of an enzyme-linked immunosorbent assay examination for anti-VZV IgM, ZSH was diagnosed, and amitriptyline improved the patient’s symptoms. Diagnosis of ZSH is challenging due to the lack of a characteristic herpes zoster rash. Physicians should be aware that ZSH can develop after mRNA vaccination. |
| first_indexed | 2024-04-14T02:00:01Z |
| format | Article |
| id | doaj.art-5bdc21df6b074abb834e3d33f06dfdaf |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-04-14T02:00:01Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-5bdc21df6b074abb834e3d33f06dfdaf2022-12-22T02:18:51ZengElsevierIDCases2214-25092022-01-0129e01563Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patientRyutaro Tanizaki0Yayoi Miyamatsu1Corresponding author.; Department of Internal Medicine and General Medicine, Ise Municipal General Hospital, 3038, Kusubecho, Ise, Mie 516-0014, JapanDepartment of Internal Medicine and General Medicine, Ise Municipal General Hospital, 3038, Kusubecho, Ise, Mie 516-0014, JapanAs a result of the COVID-19 pandemic, mRNA vaccination has become widespread. Recently, it has been suggested that instances of herpes zoster increase following mRNA COVID-19 vaccination. Herein, we describe the first case of zoster sine herpete (ZSH) after mRNA vaccination for COVID-19. A 60-year-old Japanese immunocompetent man presented with fever, fatigue, headache, cervical pain, and lumbar pain, which developed after receiving a second dose of BNT162b2 mRNA COVID-19 vaccination. Whereas most symptoms improved with symptomatic treatment, headache and numbness of the right forehead persisted in areas innervated by the trigeminal and second and third cervical nerves. Based on positive results of an enzyme-linked immunosorbent assay examination for anti-VZV IgM, ZSH was diagnosed, and amitriptyline improved the patient’s symptoms. Diagnosis of ZSH is challenging due to the lack of a characteristic herpes zoster rash. Physicians should be aware that ZSH can develop after mRNA vaccination.http://www.sciencedirect.com/science/article/pii/S2214250922001913Zoster sine herpeteCOVID-19Varicella zoster virusmRNA vaccination |
| spellingShingle | Ryutaro Tanizaki Yayoi Miyamatsu Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient IDCases Zoster sine herpete COVID-19 Varicella zoster virus mRNA vaccination |
| title | Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient |
| title_full | Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient |
| title_fullStr | Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient |
| title_full_unstemmed | Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient |
| title_short | Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient |
| title_sort | zoster sine herpete following bnt162b2 mrna covid 19 vaccination in an immunocompetent patient |
| topic | Zoster sine herpete COVID-19 Varicella zoster virus mRNA vaccination |
| url | http://www.sciencedirect.com/science/article/pii/S2214250922001913 |
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