Exosomes Derived from BM-MSCs Mitigate the Development of Chronic Kidney Damage Post-Menopause via Interfering with Fibrosis and Apoptosis

Exosomes Derived from BM-MSCs Mitigate the Development of Chronic Kidney Damage Post-Menopause via Interfering with Fibrosis and Apoptosis

The rate of chronic kidney disease (CKD) is increasing globally, and it is caused by continuous damage to kidney tissue. With time the renal damage becomes irreversible, leading to CKD development. In females, post-menopause lack of estrogen supply has been described as a risk factor for CKD develop...

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Bibliographic Details
Main Authors: Wardah A. Alasmari, Ahmed Abdelfattah-Hassan, Hanaa M. El-Ghazali, Samar A. Abdo, Doaa Ibrahim, Naser A. ElSawy, Eman S. El-Shetry, Ayman A. Saleh, Mohammed A. S. Abourehab, Hala Mahfouz
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
exosome therapy
renoprotective
nephroprotective
chronic renal injury
caspase 3
fibrosis
Online Access:https://www.mdpi.com/2218-273X/12/5/663

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